CAS: 32395-58-7; Dimethyl(Octadecyl)Silane

上下游产品

°Ctadec-1-ene dimethylmethoxysilane

专利信息

专利号:US-10730904-B2
优先权日:2012-11-14
标 题:Method for liquid-phase synthesis of nucleic acid
发明人：NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
权利人:TAKEDA PHARMACEUTICALS CO
摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

专利号:US-4919804-A
优先权日:1988-03-01
标 题:Ultrasound driven synthesis of reversed and normal phase stationary phases for liquid chromatography
发明人：DORSEY JOHN G; SENTELL KAREN B; BARNES KAREN W
权利人:UNIV FLORIDA
摘要:In a method for producing a reversed phase bonded metal oxide by reacting the metal oxide with a reactive silane, the improvement comprising conducting the reaction in the presence of ultrasonic waves.

专利号:US-7214807-B2
优先权日:2000-02-25
标 题 :Method for the preparation of fluticasone and related 17β-carbothioic esters using a novel carbothioic acid synthesis and novel purification methods
发明人：BARKALOW JUFANG; CHAMBERLIN STEVEN A; COOPER ARTHUR J; HOSSAIN AZAD; HUFNAGEL JOHN J; LANGRIDGE DENTON
权利人:ABBOTT LAB
摘要:This invention discloses a novel method for the conversion of carboxylic acids to carbothioic acids and application of the method to the preparation of androstane carbothiolates, such as fluticasone propionate, which avoids column chromatography.

专利号:US-4990602-A
优先权日:1986-12-17
标 题:Erythromycin A derivatives
发明人：MORIMOTO SHIGEO; ADACHI TAKASHI; MATSUNAGA TOHRU; KASHIMURA MASATO; ASAKA TOSHIFUMI; WATANABE YOSHIAKI; SOTA KAORU; SEKIUCHI KAZUTO
权利人:TAISHO PHARMACEUTICAL CO LTD
摘要:Erthromycin A derivatives represented by the general formula ##STR1## wherein R 1 is a group of the formula R 7 CH 2 -- (wherein R 7 is a hydrogen group or a lower alkyl group) or a group of the formula R 8 O-- (wherein R 8 is a lower alkyl group), R 2 is R 8 , a cycloalkyl group, a phenyl group or an aralkyl group.), or R 2 and R 7 together form an alkylene group, R 3 is a hydrogen atom, a lower alkyl group, a phenyl group or an aralkyl group, or R 3 and R 7 together form an alkylene group, or R 2 and R 3 together form an alkylene group, R 4 is a lower alkyl group, R 5 is a substituted silyl group, and R 6 is a hydrogen atom or R 5 , are disclosed. These compounds are useful as intermediates for the synthesis of antibacterial agents.

专利号:US-2015315229-A1
优先权日:2012-11-14
标 题 :Method for liquid-phase synthesis of nucleic acid

专利号:US-2019135852-A1
优先权日:2012-11-14
标题 :Method for liquid-phase synthesis of nucleic acid