CAS: 2557-78-0; 2-Fluorothiophenol

上下游产品

CAS号705-02-2 (2-氟苯基)硫代]乙酸 | CAS号348-54-9 邻氟苯胺 | CAS号445-29-4 邻氟苯甲酸 | CAS号492-22-8 噻吨-9-酮 | CAS号21243-09-4 3-[(2-氟苯基)硫烷基]丙酸 | CAS号1978-16-1 1-氟-2-(三氟甲基)硫代-苯 | CAS号19111-35-4 3-phenyl-4H-1λ6... | CAS号655-20-9 2-氟茴香硫醚 | CAS号7643-08-5 2-甲硫基吩噻嗪 | CAS号14135-38-7 2,2'-二氟二苯二硫醚 | CAS号1693-28-3 2-三氟甲基噻吨酮 | CAS号230-04-6 6H-Dibenzo[b,d]...

(2-氟苯基)硫代]乙酸置于高氯酸,Pyridinium Chlorochromate体系中,用 水,溶剂黄146 用作溶剂,化学反应生成2-氟苯硫酚
参考文献:Oxidative Cleavage Of S-Arylmercaptoacetic Acids By Pyridinium Chlorochromate: Kinetic And Correlation Analysis
标题:Oxidative Cleavage Of S-Arylmercaptoacetic Acids By Pyridinium Chlorochromate: Kinetic And Correlation Analysis
摘要:Kinetics Of Oxidation Of 24 S-Arylmercaptoacetic Acids (Sama) By Pyridinium Chlorochromate (Pcc) Have Been Studied In Acidmedium. The Product Of Oxidation Is The Corresponding Thiophenol. The Rate Data Of Meta-And Para-Substituted Acids Have Been Correlated Well With Sigma(I),Sigma(R)Degrees Values And The Meta-Compounds Correlate Well With F,R Values. The Reaction Constants Are Negative And Of Smaller Magnitudes. Further,The Ortho-Substituted Acids Show A Good Correlation With Triparametric Equation Involving Taft'S Sigma(I) And Sigma(R)Degrees And Charton'S Steric Parameter Nu. There Is No Considerable Steric Contribution To The Total Orthosubstituent Effect. Based On These Observations,The Mechanism Involving The Formation Of Protonated Arylsulfinylacetic Acid Intermediate,Followed By An Intramolecular Rearrangement Leading To The Product Thiophenol Has Been Proposed. (C) 1999 John Wiley & Sons,Inc.
Doi:10.1002/(Sici)1097-4601(1999)31:10<683::Aid-Jck1>3.0.Co;2-9

专利信息

专利号:US-10150160-B2
优先权日:2014-12-04
标题 :Universal one-pot and up-scalable synthesis of SERS encoded nanoparticles
发明人：PAZOS PÉREZ NICOLÃ?S; MIR DE SIMÓN BERNAT
权利人:MEDCOM ADVANCE S A; MEDCOM ADVANCE S A
摘要:The universal one-pot and up-scalable synthesis of SERS encoded nanoparticles relies on the controlled co-absorption of mercaptoundecanoic acid (MUA) and the Raman code on the metallic surfaces of the nanoparticles. In contrast to most of the reported procedures which typically involve complex steps, the present method has demonstrated to be an easy and fast one-pot approach for the production of SERS-encoded nanoparticles. This versatile strategy allows for the SERS codification of particles with every molecule with affinity toward the metal surface, independently of its chemical nature, as exemplified here in the fabrication of 31 different encoded particles using the same standard procedure. In addition to the easiness of preparation, scalability to the liter regime, stability in aqueous solutions including PBS and chemical diversity, our SERS-encoded particles show considerably higher optical efficiency than those fabricated by using PEG or PVP polymers.

专利号:US-2016318862-A1
优先权日:2013-09-25
标 题:Synthesis of delta 12-pgj3 and related compounds
发明人：NICOLAOU KYRIACOS C; HERETSCH PHILIPP; HALE CHRISTOPHER R H; EL GHZAOUI ABDELLATIF EL MARROUNI; PULUKURI KIRAN KUMAR; YU RUOCHENG; GROVE CHARLES
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present invention provides novel derivatives of Δ 12 -PGJ 3 and modular synthetic pathways to obtaining Δ 12 -PGJ 3 and derivatives thereof. In some aspects, the present derivatives of Δ 12 -PGJ 3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.

专利号:WO-0146142-A1
优先权日:1999-12-20
标题:A process for the regioselective synthesis of 2,2-dialkyl-4-substituted piperidines
发明人：HEATH PERRY CLARK
权利人:LILLY CO ELI; HEATH PERRY CLARK
摘要:The present invention provides a process for preparing a compound of formula (I): wherein R?1 and R2¿ each independently represent C¿1?-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R?-M+¿ wherein M+ is a suitable cation.

专利号:US-9481685-B2
优先权日:2008-10-02
标 题:Imaging neuroinflammation
发明人：WADSWORTH HARRY JOHN; SHAN BO; O'SHEA DENNIS; PASSMORE JOANNA MARIE; TRIGG WILLIAM JOHN
权利人:WADSWORTH HARRY JOHN; SHAN BO; O'SHEA DENNIS; PASSMORE JOANNA MARIE; TRIGG WILLIAM JOHN; GE HEALTHCARE LTD
摘要:The present invention concerns in vivo imaging and in particular in vivo imaging of the peripheral benzodiazepine receptor (PBR). A tetracyclic indole in vivo imaging agent is provided that binds with high affinity to PBR, has good uptake into the brain following administration, and which preferentially binds to tissues expressing higher levels of PBR. The present invention also provides a precursor compound useful in the synthesis of the in vivo imaging agent of the invention, as well as a method for synthesis of said in vivo imaging agent comprising use of said precursor compound, and a kit for carrying out said method. A cassette for the automated synthesis of the in vivo imaging agent is also provided. In addition, the invention provides a radiopharmaceutical composition comprising the in vivo imaging agent of the invention, as well as methods for the use of said in vivo imaging agent.

专利号:EP-3049072-A1
优先权日:2013-09-25
标 题:Synthesis of delta 12-pgj3 and related compounds

专利号:ES-2404827-T3
优先权日:2008-12-18
标 题:Procedure for the synthesis of aminomethyl-tetralin derivatives