CAS: 934162-61-5; (S)-2-(2-Fluoro-4-(Pyrrolidin-2-yl)Phenyl)-1H-Benzo[d]Imidazole-7-Carboxamide

专利信息

专利号:US-9598418-B2
优先权日:2012-12-31
标 题:Substituted phthalazin-1 (2H)-one derivatives as selective inhibitors of poly (ADP-ribose) polymerase-1
发明人：SRIVASTAVA BRIJESH K; DESAI RANJIT C; PATEL PANKAJ R
权利人:CADILA HEALTHCARE LTD
摘要:The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

专利号:US-8871765-B2
优先权日:2010-07-27
标 题 :Substituted 4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one derivatives as poly (ADP-ribose) polymerase-1 inhibitors
发明人：SHRIVASTAVA BRIJESH KUMAR
权利人:SHRIVASTAVA BRIJESH KUMAR; CADILA HEALTHCARE LTD
摘要:Disclosed are compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts. These compounds are suitable as Poly(ADP-ribose)polymerase-1 inhibitors (PARP-1 inhibitors).