CAS: 70424-69-0; 2,3,3',4,5-Pentachlorobiphenyl
该化合物是多氯联苯(PCB)家族的成员,该家族由不同程度氯化的合成有机化学品组成.多氯联苯106的特点是其化学结构,其中包括联苯所附的多氯原子,从而形成影响其物理和化学特性的复杂安排.多氯联苯对浅黄色,油性液体或固体无色,以其稳定性,耐热性和电绝缘特性而闻名.多氯联苯106与其他多氯联苯一样,具有疏水性和亲脂性,导致环境和活生物体中的生物累积性.重要的是,必须注意到多氯联苯因其长期的环境半衰期和潜在健康风险,包括致癌效应和内分泌干扰,被归类为持久性有机污染物.许多国家都实施了管制措施,限制多氯联苯(包括多氯联苯106)的生产和使用,因为其对环境和健康的影响.
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: BQENMISTWGTJIJ-UHFFFAOYSA-N
- 1S/C12H5Cl5/c13-7-3-1-2-6(4-7)8-5-9(14)11(16)12(17)10(8)15/h1-5H
- 计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
°Cta-5,7-diene-2,3-dione1,4,5,6-tetrachloro-7-(3-chlorophenyl)bicyclo2.2.2°Cta-5,7-diene-2,3-dione 3-iod°Chlorobenzene 2,3,4,5-tetrachloroiodobenzene m-chlorophenylacetylene 2,3,4,6-tetrachlorodibenzofuran 2,3,4,8-tetrachlorodibenzofuran 1,2,3,4,8-pentachlorodibenzofuran合成工艺路线路线简述
📜3-氯苯乙酮置于氢氧化钾,五氯化磷,对苯二酚体系中,用 乙醇,环己烷,苯 作为反应溶剂,化学反应 32.25H,反应生成 2,3,3',4,5-五氯联苯
参考文献:An Approach To The Synthesis Of Unsymmetrically Substituted Chlorobiphenyls
标题:An Approach To The Synthesis Of Unsymmetrically Substituted Chlorobiphenyls
摘要:
DOI:10.1021/jo00314A025
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
📝 需求与反馈
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