CAS: 5345-89-1; 3-(2,6-Dichlorophenyl)Acrylic Acid

📜丙二酸,2,6-二氯苯甲醛置于哌啶,吡啶体系中,化学反应 6.0H,反应生成 2,6-二氯肉桂酸
参考文献:银促进 α,β-不饱和羧酸的脱羧二氟亚甲基化合成烯丙基二氟化物
标题:银促进 α,β-不饱和羧酸的脱羧二氟亚甲基化合成烯丙基二氟化物
摘要:一种具有非常好官能团耐受性和广泛底物范围的有效方法可以通过银促进的芳基或烷基取代的α,β-不饱和羧酸与苯并-1,3 的脱羧偕二氟亚甲基化反应来提供具有独特e立体选择性的烯丙基二氟化物-二唑二氟甲基溴在温和的反应条件下.
DOI:10.1002/asia.202200448

专利信息

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:CN-109972166-A
优先权日:2019-04-01
标题:A method of the compound of the synthesis structure of trifluoromethyl containing vinyl