CAS: 2791-79-9; (S)-Dibenzyl 2-Aminosuccinate

上下游产品

CAS号56-84-8 L-天门冬氨酸 | CAS号100-51-6 苯甲醇 | CAS号2886-33-1 L-天冬氨酸双苄酯对甲苯磺酸盐 | CAS号5241-60-1 N-苄氧羰基-L-天冬氨酸 1... | CAS号73984-07-3 dibenzyl 2-[(4-... | CAS号6192-52-5 对甲苯磺酸一水合物 | CAS号80974-42-1 B°C-Asp(OBzl)OBzl | CAS号100-39-0 溴化苄 | CAS号13726-67-5 B°C-L-天冬氨酸 | CAS号72776-05-7 (S)-(-)-4-氧代-2-... | CAS号2177-63-1 L-天冬氨酸-β-苄酯 | CAS号16404-94-7 (S)-(-)-4-氧代-2-吖丁啶羧酸 | CAS号70853-19-9 L-Aspartic acid... | CAS号70962-64-0 1,2-bis(phenylm...

📜Di(Phenylmethyl) (2S)-2-[(Phenylmethoxy)Carbonylamino]-Butane-1,4-Dioate置于氢溴酸,溶剂黄146体系中,化学反应生成L-天冬氨酸二苄酯
参考文献:Cleavage Of N-Carbobenzoxy Groups By Dry Hydrogen Bromide And Hydrogen Chloride
标题:Cleavage Of N-Carbobenzoxy Groups By Dry Hydrogen Bromide And Hydrogen Chloride
摘要:
Doi:10.1021/jo50012A002

专利信息

专利号:US-5144073-A
优先权日:1988-08-31
标 题 :Process for preparation of dipeptides
发明人：HUBBS JOHN C
权利人:HUBBS JOHN C
摘要:Disclosed is a process for synthesis of a dipeptide such as N-acetyl-L- alpha -aspartyl-L-phenylalanine methyl ester wherein one amino acid serves as a chiral template which allows for synthesis of a second amino acid residue to form said dipeptide. The process involves several novel steps such as a nucleophile addition step. In addition, several novel intermediates are described.

专利号:US-4309346-A
优先权日:1980-03-27
标 题:Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
发明人：CHRISTENSEN BURTON G; RATCLIFFE RONALD W; SALZMANN THOMAS N
权利人:MERCK & CO INC
摘要:Disclosed is a process for the total synthesis of 1-carbapenem antibiotics (I) from L-aspartic acid via intermediates II and III: I II III wherein R is hydrogen, a pharmaceutically acceptable ester moiety or salt cation, or a readily removable blocking group; R6 and R7 are, inter alia, independently selected from the group consisting of hydrogen, alkyl, alkenyl, aryl and aralkyl; R1' is hydrogen or a protecting group; and Ra, Rb and Rc are independently selected from alkyl, aryl and aralkyl.

专利号:US-4378315-A
优先权日:1980-05-29
标题:Process for the preparation of thienamycin and intermediates
发明人：CHRISTENSEN BURTON G; RATCLIFFE RONALD W; SALZMANN THOMAS N
权利人:MERCK & CO INC
摘要:Disclosed is a process for the total synthesis of thienamycin from L-aspartic acid via intermediate III: ##STR1## R=H, blocking group or salt cation.

专利号:US-4290947-A
优先权日:1979-04-27
标 题:Process for the preparation of thienamycin and intermediates
发明人：CHRISTENSEN BURTON G; RATCLIFFE RONALD W; SALZMAN THOMAS N
权利人:MERCK & CO INC
摘要:Disclosed is a process for the total synthesis of thienamycin from L-aspartic acid via intermediate III: ##STR1## R=H, blocking group or salt cation.

专利号:US-4739048-A
优先权日:1980-05-29
标 题:Process for the preparation of thienamycin and intermediates
发明人：CHRISTENSEN BURTON G; RATCLIFFE RONALD W; SALZMANN THOMAS N
权利人:MERCK & CO INC
摘要:Disclosed is a process for the total synthesis of thienamycin from L-aspartic acid via intermediate III: ##STR1##

专利号:US-4383946-A
优先权日:1980-03-27
标题:Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
发明人：CHRISTENSEN BURTON G; RATCLIFFE RONALD W; SALZMANN THOMAS N
权利人:MERCK & CO INC
摘要:Disclosed is a process for the total synthesis of 1-carbapenem antibiotics (I) from L-aspartic acid via central intermediates II and III: I II III wherein R is hydrogen, a pharmaceutically acceptable ester moiety or salt cation, or a readily removable blocking group; R6, R7 and R8 are, inter alia, independently selected from the group consisting of hydrogen, alkyl, alkenyl, aryl and aralkyl; R1'and Re are hydrogen, or a readily removable protecting group; Ra, Rb and Rc are selected from alkyl, aryl or aralkyl.