CAS: 20835-91-0; (3S,5R,6R,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-Ethyl-6-Methylheptan-2-yl)-10,13-Dimethylhexadecahydro-5H-Cyclopenta[a]Phenanthrene-3,5,6-Triol

上下游产品

stigmast-5-en-3-yl acetate β-sitosterol dihydrogen peroxide acetic acid stigmastan-3,6-dione (24R)-3β,5α-dihydroxy-24-ethyl-5α-cholestan-6-one stigmast-4-ene-3,6-dione

📜豆甾醇置于甲酸,双氧水,Sodium Hydroxide体系中,用 甲醇 用作溶剂,化学反应 19.17H,以49%的收率获得豆甾烷-3,5,6-三醇
参考文献:Synthesis,Isolation And Characterisation Of β-Sitosterol And β-Sitosterol Oxide Derivatives
标题:Synthesis,Isolation And Characterisation Of β-Sitosterol And β-Sitosterol Oxide Derivatives
摘要:δ-谷甾醇是最常见的植物胆固醇衍生物(植物甾醇),可发生与胆固醇类似的氧化作用,生成δ-谷甾醇氧化物.植物固醇氧化物的生物影响只在植物固醇混合物(通常包括δ-谷甾醇,坎贝酯醇,豆甾醇和二氢巴西甾醇)中进行过评估.由于缺乏纯植物甾醇(包括δ-谷甾醇),因此无法收集有关单个δ-谷甾醇氧化物的重要毒性数据.本文介绍了多克纯δ-谷甾醇的高效合成路线,以及纯δ-谷甾醇氧化物的首次合成和表征.
Doi:10.1039/b505069C

专利信息

专利号:US-4923403-A
优先权日:1984-08-16
标题:Microbiological process for degradation of steroids
发明人：FERREIRA NICOLAAS P
权利人:SOUTH AFRICAN INVENTIONS
摘要:A process for preparing 3a alpha -H-4 alpha -[3'-propionic acid]-5 alpha -hydroxy-7a beta -methyl-hexahydro-1-indanone- delta -lactone, having the formula for the chemical synthesis of a pharmaceutical steroid, which includes cultivating, in the presence of cholesterol, sitosterol, stigmasterol, or a mixture of sitosterol and sitostanol, a mutant of the parent species R. australis of the genus Rhodococcus.

专利号:US-2008015374-A1
优先权日:2006-07-11
标 题 :Method for the synthesis and isolation of phytosterol esters
发明人：WILEY DAVID B; DOBBINS THOMAS A
权利人:WILEY ORGANICS INC
摘要:A process for the synthesis and isolation of phytosterol esters is described, wherein an alkali metal borohydride is used to reductively bleach tocoquinones and other chromophores in phytosterol ester trans-esterification reaction mixtures. Phytosterol esters produced by this method possess the traditional hallmarks of quality, namely bland taste and light color, and are suitable for food and pharmaceutical applications.

专利号:US-11278568-B2
优先权日:2015-07-09
标 题 :In situ preparation of cyano-bridged metal nanoparticles within a biocompatible reverse micellar system
发明人：MAUREL JEAN-CLAUDE; COMPTE ELSA; LAVAUD CYRIL; GUARI YANNICK; GUARI JOULIA; LONG JÉRÔME
权利人:MEDESIS PHARMA; CENTRE NAT RECH SCIENT; UNIV MONTPELLIER
摘要:The present invention relates to a method for in situ preparation of cyano-bridged coordination polymers as metal nanoparticles within a biocompatible reverse micellar system by mixing at least two reverse micellar systems, each one containing at least one metal salt precursor. The invention also relates to the stabilization of theses nanoparticles by using a biocompatible reverse micellar system. This system takes part of the synthesis as a nanoreactor which comprises at least an acylglycerol, a sterol, lecithin, ethanol and water for the preparation of stable cyano-bridged metal nanoparticles without any use of additional stabilizer agent.

专利号:US-2011296543-A1
优先权日:2006-06-01
标题:Nucleic acids and proteins and methods for making and using them
发明人：CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON
权利人:CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON; UNIV CALIFORNIA; CALIFORNIA INST OF TECHN; VERENIUM CORP
摘要:The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.

专利号:EP-2886657-A1
优先权日:2013-12-19
标题 :Enzymatic synthesis of phenolic acid esters and steryl phenolates
发明人：NYSTRÖM LAURA; SCHÄR ALINE
权利人:ETH ZUERICH
摘要:The present invention relates to a method for obtaining at least one steryl phenolate from at least one phenolic acid in an enzymatic process using a lipase, wherein in a first step a) the at least one phenolic acid and at least one alcohol R 1 -OH undergo an enzymatic esterification to at least one phenolic acid ester according to reaction scheme (III)n n, and in at least one second step b) the at least one phenolic acid ester and at least one sterol R 2 -OH undergo an enzymatic transesterification using a lipase to at least one steryl phenolate according to reaction scheme (IV)

专利号:US-6277431-B1
优先权日:1998-10-14
标 题 :Anticholesterolemic edible oil
发明人：BERRY CHRISTOPHER J; BIERENBAUM MARVIN L
权利人:REDEEM INC; MLB ENTPR LLC
摘要:An edible oil is provided that decreases the synthesis, absorption and blood level of cholesterol by a human patient, increases the excretion of cholesterol from the human patient, curtails accumulation of peroxidized material in the blood of the human patient, and also increases the blood level of vitamin E in said human patient.