CAS: 1746-11-8; 2-Methyl-2,3-Dihydrobenzofuran

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CAS号1746-13-0 烯丙基苯基醚 | CAS号701-06-4 1-(2-chlorophen... | CAS号78733-65-0 bis[2-(2,3-dihy... | CAS号1745-81-9 2-烯丙基酚 | CAS号7146-62-5 1-acetoxymercur... | CAS号33206-31-4 3-(2-hydroxyphe... | CAS号4265-25-2 2-甲基苯并呋喃 | CAS号122823-57-8 2-(phenyltellan... | CAS号75-83-2 2,2-二甲基丁烷 | CAS号4265-25-2 2-甲基苯并呋喃 | CAS号26210-77-5 (2-甲基-2,3-二氢-1-... | CAS号6380-21-8 2-丙烯基苯酚,顺反异构体混合物 | CAS号644-35-9 2-丙基苯酚 | CAS号102292-30-8 5-溴-2-甲基-2,3-二氢苯并呋喃 | CAS号159264-96-7 2-methyl-5-(3-p... | CAS号103261-01-4 7-Benzofurancar... | CAS号31457-03-1 2-甲基-2,3-二氢苯并呋喃-7-羧酸

📜3-烯丙基-2-羟基苯甲酸甲酯置于苯胺体系中,化学反应生成2,3-二氢-2-甲基苯并呋喃
参考文献:Claisen,Justus Liebigs Annalen Der Chemie,1919,Vol. 418,P. 102
标题:Claisen,Justus Liebigs Annalen Der Chemie,1919,Vol. 418,P. 102

专利信息

专利号:US-7678948-B2
优先权日:2006-06-30
标 题:Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof
发明人：THIRUVENGADAM TIRUVETTIPURAM K; WANG TAO; CHIU JOHN S; LIAO JING
权利人:SCHERING CORP
摘要:This application discloses provides a process for the introduction of nitro-group functionality into a compound which contains also a site of unsaturation and/or oxygen functionality by direct (one step) oxidation of an oxime functional group mediated by a molybdenum VI/VII peroxo complex, the process comprising:n (a) providing a substrate of Formula I containing an oxime functional group; nn n n n n n n n n n n n n n wherein R 1 and R 2 are selected independently from linear, branched or cyclic alkyl and linear, branched or cyclic alkenyl groups, optionally substituted, with the proviso that at least one of R 1 or R 2 contains a carbon/carbon double bond; and n n n (b) contacting said substrate of Formula I with a molybdenum oxidation complex, thereby oxidizing said oxime functional group to a nitro functional group to yield the structure of Formula III. n n n n n nWhere R 1 and R 2 are as defined above.

专利号:US-7553987-B2
优先权日:2006-06-30
标 题:Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof

专利号:US-2008009651-A1
优先权日:2006-06-30
标题:Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof

专利号:US-2009203936-A1
优先权日:2006-06-30
标题 :Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof

专利号:WO-2011161615-A1
优先权日:2010-06-24
标题 :5-lipoxygenase inhibitors
发明人：VERMA ASHWANI KUMAR; MALHOTRA SANJAY; MARIMGANTI SRINIVASA; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
权利人:RANBAXY LAB LTD; VERMA ASHWANI KUMAR; MALHOTRA SANJAY; MARIMGANTI SRINIVASA; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
摘要:The present invention relates to pyrazole derivatives of formula 1 and to process as for their synthesis as 5-lipoxygenase (5-LO) inhibitors. The present invention also relates to pharmacological compositions containing these pyrazole derivatives, as well as, methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.

专利号:WO-2022265577-A2
优先权日:2021-06-15
标题:Coronavirus enzyme modulators, methods of synthesis and uses thereof