CAS: 13154-25-1; Chlorotriisobutylsilane

该化合物是一种多用途有机硅化合物,其特点是活性氯硅基组和分支烷基替代成分,其结构具有较有利的特性,例如,与线性模拟相比,它增加了消毒障碍,提高了水解稳定性,该化合物通常用作聚合物和复合应用中的混合剂或表面修饰剂,它促进有机和无机阶段之间的粘合;异丁基组的存在有助于减少挥发性和受控制的再活动,使之适合精确配方;还用于特殊化学合成,特别是在需要定制的疏离水或功能化的情况下;建议由于对湿度敏感,在惰性条件下进行适当处理.

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    专利信息


    专利号:US-7572916-B2
    优先权日:2004-05-03
    标 题 :Diastereoselective synthesis process with 6-bromo-4-(3-chlorophenyl)-2-methoxy-quinoline
    发明人:FILLIERS WALTER FERDINAND MARIA; BROECKX RUDY LAURENT MARIA; ANGIBAUD PATRICK RENE
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:A diastereoselective synthesis process for the preparation of (R)-(+)-6-[amino(4chlorophenyl)(1-methyl-1H-imidazol-5-yl) methyl]-4-(3-chlorophenyl)-1-methyl2(1H)-quinolinone which comprises the preparation of a compound of formula (XVII): and the stereochemically isomeric forms thereof wherein R is C1-6alkyl or C1-6alkylphenyl.

    专利号:US-7456287-B2
    优先权日:2004-05-03
    标 题:Diastereoselective synthesis process for the preparation of imidazole compounds
    发明人:FILLIERS WALTER FERDINAND MARIA; BROECKX RUDY LAURENT MARIA; ANGIBAUD PATRICK RENE
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:A diastereoselective synthesis process for the preparation of an enantiomer of 6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone which comprises the conversion of (±)-6-[chloro(4-chlomphenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone into a compound of formula (VIII) wherein aryl is phenyl substituted once or twice with C 1-6 alkyloxy or naphtalenyl substituted once or twice with C 1-6 alkyloxy.

    专利号:US-5665882-A
    优先权日:1994-03-14
    标题 :Pyridyl ethylation of lactams
    发明人:CHUNG JOHN Y L; ZHAO DALIAN; MCNAMARA JAMES M; HUGHES DAVID L
    权利人:MERCK & CO INC
    摘要:PCT No. PCT/US94/12671 Sec. 371 Date Aug. 29, 1996 Sec. 102(e) Date Aug. 29, 1996 PCT Filed Nov. 7, 1994 PCT Pub. No. WO95/25101 PCT Pub. Date Sep. 21, 1995The invention is a highly efficient synthesis for making compounds of formula: wherein n=0, 1, R is C1-4 alkyl or benzyl; and R1, when present, is C1-4 alkyl, OH, O-C1-4 alkyl or S-C1-4 alkyl. The process involves silane-mediated conjugation of 4-vinylpyridine to a substituted lactam.

    专利号:US-5202444-A
    优先权日:1990-11-27
    标题:Optically isomeric inositol and process for making optically active compound
    发明人:OZAKI SHOICHIRO; AKIYAMA TAKAHIKO; KAGEYAMA KUNIO; MACHIDA MORIHISA
    权利人:YOKOHAMA RUBBER CO LTD
    摘要:Optically active diols and hydroxycarboxylic acids and their esters are produced by deriving 1L-1,2:5,6-di-O-cyclohexylidene-chiro-inositol from 1L-chiro-inositol as an asymmetric source, followed by introduction of a selected class of sterically hindering and asymmetrically reactive groups into the first-mentioned compound and by subsequent reduction of the resulting compound. Seven specific inositols are also derivable from synthesis of those ultimate compounds.

    专利号:US-7524961-B2
    优先权日:2004-05-03
    标题 :Diastereoselective addition of lithiated N-methylimidazole on sulfinimines
    发明人:FILLIERS WALTER FERDINAND MARIA; BROECKX RUDY LAURENT MARIA; ANGIBAUD PATRICK RENE
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:A diastereoselective synthesis process for the preparation of (R)-(+)-6-[amino(4-chlorophenyl) (1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2 (1H)-quinolinone which comprises the preparation of a compound of formula (VIII) n nand the stereochemically isomeric forms thereof wherein R is C 1-6 alkyl or C 1-6 alkylphenyl-.

    专利号:US-9416147-B2
    优先权日:2014-04-03
    标题 :Preparation of silazane compound
    发明人:TONOMURA YOICHI; KUBOTA TOHRU
    权利人:SHINETSU CHEMICAL CO
    摘要:A silazane compound useful as synthesis intermediates for paint additives, polymer modifiers, pharmaceuticals and agricultural chemicals is efficiently prepared by reaction of a halosilane compound with an amino-containing compound in a solvent which is the same silazane compound as the target product.
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    主要参考文献

    参考标题:Asymmetric Synthesis Of 2-Alkyl(Aryl)-2,3-Dihydro-4-Pyridones By Addition Of Grignard Reagents To Chiral 1-Acyl-4-Methoxypyridinium Salts
    作者:Daniel L. Comins,Sajan P. Joseph,R. Richard Goehring |发布日期:1994.6
    摘要:Grignard Addition To A Chiral 1-Acyl-4-Methoxypyridinium Salt Provides Synthetically Useful 2-Alkyl(Aryl)-2,3-Dihydro-4-Pyridones In High Diastereomeric Excess

    合成参考文献


    摘要:Pietruszka, J., Science of Synthesis, (2002) 4, 168.
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