专利号:US-2007128658-A1 优先权日:2005-11-14 标 题:Fluorescent dyes, methods and uses thereof 发明人:BLACKWELL HELEN E; BOWMAN MATTHEW D 权利人:BLACKWELL HELEN E; BOWMAN MATTHEW D 摘要:The present invention provides a method for identifying and characterizing candidate fluorescent molecules. This method involves the generation of spatially addressed arrays of heterocyclic compounds which are candidate fluorescent molecules. The spatially addressed array can be used to identify fluorescent molecules among the candidate molecules. The spatially addressed array can be used to determine the optical characteristics of one more candidate molecules. The invention also provides methods for making such arrays of heterocyclic compounds. In a specific embodiment, synthetic methods are provided for synthesis of triarylpyridines, particularly unsymmetric triarylpyridines. n preferred embodiments, the present invention provides novel heterocyclic fluorescent compounds having deazalumazine, cyanopyridine or pyrimidine cores. Heterocyclic fluorescent compounds of this invention are useful as dyes to label molecules such as nucleic acids, peptides and proteins, and particularly antibodies. In other embodiments, the novel heterocyclic fluorescent compounds are useful as dyes to label cellular compartments and organelles. The novel heterocyclic fluorescent compounds can also be used as sensors or indicators of specific metal ions, chemical warfare agents and pH.
专利号:RU-2130930-C1 优先权日:1993-08-23 标题:Method of synthesis of pyrazole and its derivatives
专利号:CN-108203408-B 优先权日:2018-03-12 标 题 :A kind of pyrazole compound containing N-aryl sulfonate and its synthesis and application
专利号:CN-103086970-A 优先权日:2013-01-09 标题 :Synthesis, preparation method and antibacterial and anticancer effects of a class of 3,5-diphenyl-2H-pyrazole derivatives with trifluoromethylphenyl
专利号:CN-102702062-A 优先权日:2012-07-04 标题 :Synthesis, preparation method and anticancer effect of a class of 3,5-diphenyl-2H-pyrazole derivatives
摘要:Weibel, J.-M.; Blanc, A.; Pale, P., Science of Synthesis Knowledge Updates, (2018) 1, 14. 摘要:Götzinger, A. C.; Müller, T. J. J., Science of Synthesis Knowledge Updates, (2017) 3, 107. 摘要:Götzinger, A. C.; Müller, T. J. J., Science of Synthesis Knowledge Updates, (2017) 3, 82. 摘要:Götzinger, A. C.; Müller, T. J. J., Science of Synthesis Knowledge Updates, (2017) 3, 113. 摘要:Götzinger, A. C.; Müller, T. J. J., Science of Synthesis Knowledge Updates, (2017) 3, 52.