CAS: 933-20-0; 4,6-Dichloro-1,3,5-Triazin-2-Amine

上下游产品

CAS号108-77-0 氰尿酰氯 | CAS号1336-21-6 氨水 | CAS号7664-41-7 氨 | CAS号67-64-1 丙酮 | CAS号123-91-1 1,4-二氧六环 | CAS号629-14-1 1,2-二乙氧基乙烷 | CAS号32998-04-2 6-氯-N,N-二甲基-1,3... | CAS号189250-15-5 N-苄-6-氯-1,3,5-三... | CAS号30377-20-9 2-N,4-N-dimethy... | CAS号6190-65-4 去乙基阿特拉津 | CAS号645-93-2 三聚氰胺一酰胺 | CAS号7440-44-0 活性炭 | CAS号16007-72-0 6-chloro-2-N-ph... | CAS号1007-28-9 氟氯氢菊脂 | CAS号16370-63-1 2-氨基-4,6-甲氧基-1,... | CAS号64887-39-4 2-[(4-氨基-6-氯-1,...

📜三聚氯氰置于氨体系中,用 水,丙酮 作为反应溶剂,以93%的收率获得产物2-氨基-4,6-二氯-S-三嗪
参考文献:N-甲基三聚氰胺:合成,表征和物理性质
标题:N-甲基三聚氰胺:合成,表征和物理性质
摘要:作为生产改性三聚氰胺甲醛树脂和其他聚合物构件的有价值的化合物,N-甲基三聚氰胺最近已变得越来越重要.这些聚合物的一大优点是减少了致癌的甲醛.选择聚合过程(例如,物质聚合,溶液中的聚合)并控制聚合反应和这些新型材料的性能,需要了解用作新结构单元的三聚氰胺衍生物的性能.n的所有可能排列制备了甲基三聚氰胺,并通过gc / Ms监测反应进程.制备2,4,6-Tris(二甲基氨基)-1,3,5-三嗪以完成该系列;然而,这也是各种合成路线中可能的副产物.优化反应条件以获得具有尽可能高纯度的每种衍生物的高产率.通过NMR和ir光谱,质谱,元素分析和单晶x射线衍射对这些物质进行表征.另外,测定了物理性质,例如溶解度,熔点和p K B值.氨基,甲基氨基和二甲基氨基的数目对这些性质具有显着影响.总而言之,我们发现通过增加氨基和甲基氨基的数量,溶解度和p Kb增加.随着氨基数目的增加,化合物趋于形成氢键,因此,熔点转移至它们开始分解的较高温度范围.
DOI:10.1021/acs.Joc.6B00355

专利信息

专利号:US-2023220001-A1
优先权日:2020-06-09
标 题:Method for synthesis of thioether-containing peptides
发明人：GRUSS HENDRIK; LUTZ CHRISTIAN; SÃœSSMUTH RODERICH; Yao guiyang; KNITTEL CAROLINE; KOSOL SIMONE; MAINZ ANDI
权利人:HEIDELBERG PHARMA RES GMBH
摘要:The present invention relates to a method of formation of a sulphur bridge between tryptophan and cysteine in solid phase peptide synthesis under iodine treatment. The invention also relates to the resulting compounds of the method and their respective use.

专利号:WO-2023086801-A1
优先权日:2021-11-09
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-7179906-B2
优先权日:1996-04-01
标 题 :Asymmetric benzoxanthene dyes
发明人：BENSON SCOTT C; MENCHEN STEVEN M; THEISEN PETER D; HENNESSEY KEVIN M; FURNISS VERGINE C; HAUSER JOAN D
权利人:APPLERA CORP
摘要:A class of asymmetric monobenzoxanthene compounds useful as fluorescent dyes are disclosed having the structure n nwherein Y 1 and Y 2 are individually hydroxyl, amino, imminium, or oxygen, R 1 –R 8 are hydrogen, fluorine, chlorine, alkyl, alkene, alkyne, sulfonate, amino, amido, nitrile, alkoxy, linking group, and combinations thereof, and R 9 is acetylene, alkane, alkene, cyano, substituted phenyl, and combinations thereof. The invention further includes novel intermediate compounds useful for the synthesis of asymmetric benzoxanthene compounds having the general structuren n nwhere substituents R 3 –R 7 correspond to like-referenced substituents in the structure of described above, and Y 2 is hydroxyl or amine. In another aspect, the invention includes methods for synthesizing the above dye compounds and intermediates. In yet another aspect, the present invention includes reagents labeled with the asymmetric benzoxanthene dye compounds, including deoxynucleotides, dideoxynucleotides, phosphoramidites, and polynucleotides. In an additional aspect, the invention includes methods utilizing such dye compounds and reagents including dideoxy polynucleotide sequencing and fragment analysis methods.

专利号:US-2007042401-A1
优先权日:2003-12-17
标题 :Methods for synthesis of encoded libraries

专利号:US-8221719-B2
优先权日:2007-09-05
标 题:Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof
发明人：PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI
权利人:PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.

专利号:US-8143057-B2
优先权日:2003-12-18
标题 :Chelating agents and highly luminescent and stable chelates and their use
发明人：HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI
权利人:HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.