CAS: 83945-57-7; (1R,4Ar,5S,8Ar)-1,4A-Dimethyl-6-Methylene-5-[(2E)-3-Methyl-2,4-Pe Ntadien-1-Yl]Decahydro-1-Naphthalenecarboxylic Acid

该化合物是一种自然产生的有机化合物,被归类为苯酚酸,它来自各种植物来源,以潜在的生物活动而著称,包括抗氧化剂和抗炎特性.4-乙基苯丙酸结构为一种碳酸基酸功能组和苯丙基氢氧基组,有助于其再活和与生物系统互动.该化合物经常被研究其在植物代谢方面的作用及其对人类营养的潜在健康惠益.此外,它可能表现出抗微生物特性,使其在食品保护和药理应用方面引起兴趣.与许多苯丙酸化合物一样,其在水中的溶解性有限,但可溶解于有机溶剂中,影响其提取和在各种应用中的利用.

英文名称(1R,4Ar,5S,8Ar)-1,4A-Dimethyl-6-Methylene-5-[(2E)-3-Methyl-2,4-Pe Ntadien-1-Yl]Decahydro-1-Naphthalenecarboxylic Acid
中文名称4-表可木酸
CAS编号83945-57-7
MFCD编号:MFCD20274618
分子式:C20H30O2分子量:302.45
产品CID: 1827788
产品分类天然产物 → 萜类

相似结构搜索
InChIKey: YGBZFOQXPOGACY-RIYZIHGNSA-N
1S/C20H30O2/c1-6-14(2)8-10-16-15(3)9-11-17-19(16,4)12-7-13-20(17,5)18(21)22/h6,8,16-17H,1,3,7,9-13H2,2,4-5H3,(H,21,22)/b14-8+/t16-,17+,19+,20+/m0/s1
计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数4.0

物理性质

沸点414.0±34.0 °C at 760 mmHg
闪点199.8±20.3 °C
密度1.0±0.1 g/cm3
PSA:37.3
LogP:6.69
折射率1.520
蒸汽压0.0±2.1 mmHg at 25°C
溶解性Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
外观形态粉末
储存条件2-8°C，干燥环境，密闭

MSDS等安全信息

危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
防范说明P264+P280+P305+P351+P338+P337+P313
危险品标志Xi
安全声明H303+H313+H333

合成工艺路线路线简述

70224-44-1 = 83945-57-7
反应条件:1.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

203319-77-1 = 83945-57-7
反应条件:1.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt1.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

24720-64-7 = 83945-57-7
反应条件:1.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C2.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C2.2 Solvents: Tetrahydrofuran; 1 H,-78 °C2.3 Reagents: Sodium Bicarbonate Solvents: Water3.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt3.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

24720-64-7 = 83945-57-7
反应条件:1.1 Solvents: Toluene; Rt; 24 H,110 °C2.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C2.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt2.3 Reagents: Ammonium Chloride Solvents: Water; Rt3.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt3.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

= 83945-57-7
反应条件:1.1 Reagents: Triethylsilane Catalysts: Palladium,Water Solvents: Tetrahydrofuran; Overnight,Rt2.1 Solvents: Toluene; Rt; 24 H,110 °C3.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C3.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt3.3 Reagents: Ammonium Chloride Solvents: Water; Rt4.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt4.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

= 83945-57-7
反应条件:1.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C1.2 Reagents: Sodium Bicarbonate Solvents: Water2.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C2.2 Reagents: Hydrochloric Acid Solvents: Water3.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C4.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C4.2 Solvents: Tetrahydrofuran; 1 H,-78 °C4.3 Reagents: Sodium Bicarbonate Solvents: Water5.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt5.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

= 83945-57-7
反应条件:1.1 Reagents: 1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Catalysts: 4-(Dimethylamino)Pyridine Solvents: Dichloromethane; 0 °C -> Rt; Overnight,Rt1.2 Reagents: Ammonium Chloride Solvents: Water; Rt2.1 Reagents: Triethylsilane Catalysts: Palladium,Water Solvents: Tetrahydrofuran; Overnight,Rt3.1 Solvents: Toluene; Rt; 24 H,110 °C4.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C4.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt4.3 Reagents: Ammonium Chloride Solvents: Water; Rt5.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt5.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

1235-74-1 = 83945-57-7
反应条件:1.1 Reagents: 1,1,1,3,3,3-Hexafluoro-2-Propanol,2,3-Benzodioxin-1,4-Dione; Rt; 12 H,40 °C; 40 °C -> Rt1.2 Reagents: Sodium Bicarbonate Solvents: Methanol,Water; 6 H,40 °C1.3 Solvents: Water; Ph 72.1 Reagents: Ozone Solvents: Methanol,Dichloromethane; 1.5 H,-78 °C2.2 Reagents: Zinc Solvents: Acetic Acid; 2.5 H,Rt2.3 Reagents: 1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Catalysts: 4-(Dimethylamino)Pyridine Solvents: Dichloromethane; 0 °C -> Rt; Overnight,Rt2.4 Reagents: Ammonium Chloride Solvents: Water; Rt3.1 Reagents: Triethylsilane Catalysts: Palladium,Water Solvents: Tetrahydrofuran; Overnight,Rt4.1 Solvents: Toluene; Rt; 24 H,110 °C5.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C5.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt5.3 Reagents: Ammonium Chloride Solvents: Water; Rt6.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt6.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

1740-19-8 = 83945-57-7
反应条件:1.1 Reagents: Potassium Carbonate Solvents: Acetone; Overnight,Rt2.1 Reagents: 1,1,1,3,3,3-Hexafluoro-2-Propanol,2,3-Benzodioxin-1,4-Dione; Rt; 12 H,40 °C; 40 °C -> Rt2.2 Reagents: Sodium Bicarbonate Solvents: Methanol,Water; 6 H,40 °C2.3 Solvents: Water; Ph 73.1 Reagents: Ozone Solvents: Methanol,Dichloromethane; 1.5 H,-78 °C3.2 Reagents: Zinc Solvents: Acetic Acid; 2.5 H,Rt3.3 Reagents: 1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Catalysts: 4-(Dimethylamino)Pyridine Solvents: Dichloromethane; 0 °C -> Rt; Overnight,Rt3.4 Reagents: Ammonium Chloride Solvents: Water; Rt4.1 Reagents: Triethylsilane Catalysts: Palladium,Water Solvents: Tetrahydrofuran; Overnight,Rt5.1 Solvents: Toluene; Rt; 24 H,110 °C6.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C6.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt6.3 Reagents: Ammonium Chloride Solvents: Water; Rt7.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt7.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

1779-49-3 = 83945-57-7
反应条件:1.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C1.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt1.3 Reagents: Ammonium Chloride Solvents: Water; Rt2.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt2.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

1779-49-3 + 212331-27-6 = 83945-57-7
反应条件:1.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C1.2 Solvents: Tetrahydrofuran; 1 H,-78 °C1.3 Reagents: Sodium Bicarbonate Solvents: Water2.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt2.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

1612188-61-0 = 83945-57-7
反应条件:1.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C1.2 Reagents: Hydrochloric Acid Solvents: Water2.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C3.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C3.2 Solvents: Tetrahydrofuran; 1 H,-78 °C3.3 Reagents: Sodium Bicarbonate Solvents: Water4.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt4.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

13742-23-9 = 83945-57-7
反应条件:1.1 Reagents: Ozone Solvents: Methanol,Dichloromethane; 1.5 H,-78 °C1.2 Reagents: Zinc Solvents: Acetic Acid; 2.5 H,Rt1.3 Reagents: 1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Catalysts: 4-(Dimethylamino)Pyridine Solvents: Dichloromethane; 0 °C -> Rt; Overnight,Rt1.4 Reagents: Ammonium Chloride Solvents: Water; Rt2.1 Reagents: Triethylsilane Catalysts: Palladium,Water Solvents: Tetrahydrofuran; Overnight,Rt3.1 Solvents: Toluene; Rt; 24 H,110 °C4.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C4.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt4.3 Reagents: Ammonium Chloride Solvents: Water; Rt5.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt5.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

13742-23-9 = 83945-57-7
反应条件:1.1 Reagents: Ozone Solvents: Methanol,Dichloromethane; 1.5 H,-78 °C1.2 Reagents: Zinc Solvents: Acetic Acid; 2.5 H,Rt2.1 Reagents: 1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide Hydrochloride Catalysts: 4-(Dimethylamino)Pyridine Solvents: Dichloromethane; 0 °C -> Rt; Overnight,Rt2.2 Reagents: Ammonium Chloride Solvents: Water; Rt3.1 Reagents: Triethylsilane Catalysts: Palladium,Water Solvents: Tetrahydrofuran; Overnight,Rt4.1 Solvents: Toluene; Rt; 24 H,110 °C5.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 1 H,0 °C5.2 Solvents: Tetrahydrofuran; 0 °C -> Rt; 2 H,Rt5.3 Reagents: Ammonium Chloride Solvents: Water; Rt6.1 Reagents: Potassium Hydroxide,Lithium Hydroxide Solvents: Methanol,Water; 24 H,Reflux; Reflux -> Rt6.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
标题:A Chiral Pool Approach For Asymmetric Syntheses Of (-)-Antrocin,(+)-Asperolide C,And (-)-Trans-Ozic Acid
作者:Li,Fu-Zhuo; Et Al
参考文献:Chemical Communications (Cambridge 日期:2016 卷标:52(84) 页码:12426-12429]

6638-79-5 = 83945-57-7
反应条件:1.1 Reagents: Chloro(1-Methylethyl)Magnesium Solvents: Tetrahydrofuran; -78 °C -> 0 °C; 30 Min,0 °C1.2 Reagents: Sodium Bicarbonate Solvents: Water2.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C2.2 Reagents: Sodium Bicarbonate Solvents: Water3.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C3.2 Reagents: Hydrochloric Acid Solvents: Water4.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C5.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C5.2 Solvents: Tetrahydrofuran; 1 H,-78 °C5.3 Reagents: Sodium Bicarbonate Solvents: Water6.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt6.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

= 83945-57-7
反应条件:1.1 Reagents: Sodium Periodate,Ruthenium Trichloride Solvents: Carbon Tetrachloride,Acetonitrile,Water; 2 H,Ph 7,22 °C2.1 Reagents: Chloro(1-Methylethyl)Magnesium Solvents: Tetrahydrofuran; -78 °C -> 0 °C; 30 Min,0 °C2.2 Reagents: Sodium Bicarbonate Solvents: Water3.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C3.2 Reagents: Sodium Bicarbonate Solvents: Water4.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C4.2 Reagents: Hydrochloric Acid Solvents: Water5.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C6.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C6.2 Solvents: Tetrahydrofuran; 1 H,-78 °C6.3 Reagents: Sodium Bicarbonate Solvents: Water7.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt7.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

= 83945-57-7
反应条件:1.1 Reagents: Hydrazine Solvents: Diethylene Glycol; 22 °C -> 160 °C; 2 H,160 °C; 160 °C -> 22 °C1.2 Reagents: Potassium Hydroxide; 22 °C -> 180 °C; 4 H,180 °C; 180 °C -> 22 °C1.3 Reagents: Hydrochloric Acid Solvents: Water2.1 Reagents: Sodium Periodate,Ruthenium Trichloride Solvents: Carbon Tetrachloride,Acetonitrile,Water; 2 H,Ph 7,22 °C3.1 Reagents: Chloro(1-Methylethyl)Magnesium Solvents: Tetrahydrofuran; -78 °C -> 0 °C; 30 Min,0 °C3.2 Reagents: Sodium Bicarbonate Solvents: Water4.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C4.2 Reagents: Sodium Bicarbonate Solvents: Water5.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C5.2 Reagents: Hydrochloric Acid Solvents: Water6.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C7.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C7.2 Solvents: Tetrahydrofuran; 1 H,-78 °C7.3 Reagents: Sodium Bicarbonate Solvents: Water8.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt8.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

3587-60-8 = 83945-57-7
反应条件:1.1 Reagents: Potassium Tert-Butoxide Solvents: Tert-Butanol; 15 Min,22 °C1.2 Reagents: Sodium Bicarbonate Solvents: Water1.3 Reagents: Hydrochloric Acid Solvents: Tetrahydrofuran,Water; 1 H,22 °C2.1 Reagents: Hydrazine Solvents: Diethylene Glycol; 22 °C -> 160 °C; 2 H,160 °C; 160 °C -> 22 °C2.2 Reagents: Potassium Hydroxide; 22 °C -> 180 °C; 4 H,180 °C; 180 °C -> 22 °C2.3 Reagents: Hydrochloric Acid Solvents: Water3.1 Reagents: Sodium Periodate,Ruthenium Trichloride Solvents: Carbon Tetrachloride,Acetonitrile,Water; 2 H,Ph 7,22 °C4.1 Reagents: Chloro(1-Methylethyl)Magnesium Solvents: Tetrahydrofuran; -78 °C -> 0 °C; 30 Min,0 °C4.2 Reagents: Sodium Bicarbonate Solvents: Water5.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C5.2 Reagents: Sodium Bicarbonate Solvents: Water6.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C6.2 Reagents: Hydrochloric Acid Solvents: Water7.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C8.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C8.2 Solvents: Tetrahydrofuran; 1 H,-78 °C8.3 Reagents: Sodium Bicarbonate Solvents: Water9.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt9.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

= 83945-57-7
反应条件:1.1 Reagents: Ozone Solvents: Dichloromethane; -78 °C1.2 Reagents: Triphenylphosphine; -78 °C -> 22 °C; 4 H,22 °C2.1 Reagents: Potassium Tert-Butoxide Solvents: Tert-Butanol; 15 Min,22 °C2.2 Reagents: Sodium Bicarbonate Solvents: Water2.3 Reagents: Hydrochloric Acid Solvents: Tetrahydrofuran,Water; 1 H,22 °C3.1 Reagents: Hydrazine Solvents: Diethylene Glycol; 22 °C -> 160 °C; 2 H,160 °C; 160 °C -> 22 °C3.2 Reagents: Potassium Hydroxide; 22 °C -> 180 °C; 4 H,180 °C; 180 °C -> 22 °C3.3 Reagents: Hydrochloric Acid Solvents: Water4.1 Reagents: Sodium Periodate,Ruthenium Trichloride Solvents: Carbon Tetrachloride,Acetonitrile,Water; 2 H,Ph 7,22 °C5.1 Reagents: Chloro(1-Methylethyl)Magnesium Solvents: Tetrahydrofuran; -78 °C -> 0 °C; 30 Min,0 °C5.2 Reagents: Sodium Bicarbonate Solvents: Water6.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C6.2 Reagents: Sodium Bicarbonate Solvents: Water7.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C7.2 Reagents: Hydrochloric Acid Solvents: Water8.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C9.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C9.2 Solvents: Tetrahydrofuran; 1 H,-78 °C9.3 Reagents: Sodium Bicarbonate Solvents: Water10.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt10.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188]

= 83945-57-7
反应条件:1.1 Reagents: Boron Trifluoride Etherate Solvents: Dichloromethane; 0 °C -> 22 °C; 2.5 H,22 °C1.2 Reagents: Sodium Bicarbonate Solvents: Water2.1 Reagents: Ozone Solvents: Dichloromethane; -78 °C2.2 Reagents: Triphenylphosphine; -78 °C -> 22 °C; 4 H,22 °C3.1 Reagents: Potassium Tert-Butoxide Solvents: Tert-Butanol; 15 Min,22 °C3.2 Reagents: Sodium Bicarbonate Solvents: Water3.3 Reagents: Hydrochloric Acid Solvents: Tetrahydrofuran,Water; 1 H,22 °C4.1 Reagents: Hydrazine Solvents: Diethylene Glycol; 22 °C -> 160 °C; 2 H,160 °C; 160 °C -> 22 °C4.2 Reagents: Potassium Hydroxide; 22 °C -> 180 °C; 4 H,180 °C; 180 °C -> 22 °C4.3 Reagents: Hydrochloric Acid Solvents: Water5.1 Reagents: Sodium Periodate,Ruthenium Trichloride Solvents: Carbon Tetrachloride,Acetonitrile,Water; 2 H,Ph 7,22 °C6.1 Reagents: Chloro(1-Methylethyl)Magnesium Solvents: Tetrahydrofuran; -78 °C -> 0 °C; 30 Min,0 °C6.2 Reagents: Sodium Bicarbonate Solvents: Water7.1 Reagents: Pyridine,Thionyl Chloride Solvents: Dichloromethane; 1 H,-78 °C7.2 Reagents: Sodium Bicarbonate Solvents: Water8.1 Reagents: Diisobutylaluminum Hydride Solvents: Tetrahydrofuran; 1 H,-78 °C8.2 Reagents: Hydrochloric Acid Solvents: Water9.1 Solvents: Toluene; 22 °C -> 110 °C; 22 H,110 °C10.1 Reagents: Butyllithium Solvents: Hexane; 30 Min,0 °C; 0 °C -> -78 °C10.2 Solvents: Tetrahydrofuran; 1 H,-78 °C10.3 Reagents: Sodium Bicarbonate Solvents: Water11.1 Reagents: 2-Methyl-2-Butene,Sodium Chlorite Catalysts: 2-Azatricyclo[3.3.1.13,7]Dec-2-Yloxy Solvents: Acetic Acid,Dichloromethane,Water; 24 H,Ph 4.6,Rt11.2 Reagents: Sodium Bisulfite Solvents: Water
标题:Total Synthesis Of Taiwaniadducts B,C,And D
作者:Deng,Jun; Et Al
参考文献:Journal Of The American Chemical Society 日期:2014 卷标:136(23) 页码:8185-8188