CAS: 64178-58-1; 4-Chloro-5-Hydroxypyridazin-3(2H)-One

相似化合物

1677-79-8 6641-32-3 1245643-70-2

上下游产品

4,5-dichloro-2H-pyridazin-3-one 4-chloro-5-methoxypyridazin-3-(2H)-one 3,4-dichloro-5-methoxy-pyridazine 5-hydroxy-3(2H)-pyridazinone

📜4,5-二氯-3-羟基哒嗪置于氢氧化钾体系中,化学反应 6.0H,以54%的收率获得产物4-氯-5-羟基3(2H)-哒嗪
参考文献:Pyridazines With Heteroatom Substituents In Position 3 And 5,Part 1: 5-Hydroxy-3(2H)-Pyridazinone And Its Derivatives
标题:Pyridazines With Heteroatom Substituents In Position 3 And 5,Part 1: 5-Hydroxy-3(2H)-Pyridazinone And Its Derivatives
摘要:
DOI:10.1007/bf00811746

专利信息

专利号:US-9603951-B2
优先权日:2010-02-08
标题 :Methods and apparatus for synthesizing imaging agents, and intermediates thereof
发明人：LAZEWATSKY JOEL; DEVINE MARYBETH
权利人:LANTHEUS MEDICAL IMAGING INC
摘要:The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18 F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.