CAS: 622-39-9; 2-Propylpyridine

该化合物是一种环环有机化合物,其特点是在2位置用丙基组替代了一条环,这在有机溶剂中可以溶解,并且显示出典型的衍生物的基本特性,它作为制药和农用化学合成的多种中间体,特别是在开发活性成分和特殊化学品方面,它的结构性特性使它在协调化学和催化过程中对离心设计有用.该化合物的特点是具有中度的再活动性,允许选择性的功能化.由于其易燃性和潜在刺激效应,需要妥善处理.建议在惰性条件下进行储存以保持稳定性.

结构式图片

相似化合物

2294-76-0 1129-69-7 5058-19-5

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合成工艺路线路线简述

    Gamma-去氢毒芹碱置于n-氯代丁二酰亚胺,Sodium Methylate体系中,用 甲醇,四氯化碳 作为反应溶剂,化学反应 15.0H,反应生成 2-丙基吡啶
    参考文献:A New Efficient Synthesis Of Pyridines
    标题:A New Efficient Synthesis Of Pyridines
    摘要:循环六元亚胺,即2,3,4,5-四氢吡啶,在温和条件下通过与氯代琥珀酰亚胺(ncs)进行高度区域选择性的α,α-二氯化转化为相应的吡啶,随后与甲醇碱进行双重脱氯化反应,效率很高.
    DOI:10.1039/cc9960000635

    海关参考信息

    专利信息


    专利号:US-7825244-B2
    优先权日:2005-06-10
    标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
    发明人:BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

    专利号:US-4801744-A
    优先权日:1985-03-01
    标 题 :Catalytic synthesis of urea from carbon monoxide and amine compound
    发明人:HERMAN JEAN-JACQUES; LECLOUX ANDRE
    权利人:SOLVAY
    摘要:Process for the catalytic synthesis of nitrogen-containing organic compounds, comprising the reaction of carbon monoxide with at least one amino compound in a reaction mixture containing a catalyst based on selenium and a substituted pyridine. The process is particularly suitable for the synthesis of ureas and of their polymers.

    专利号:US-6399536-B2
    优先权日:2000-02-11
    标 题 :High performance catalyst systems for the synthesis of alkylenecarbonates
    发明人:KIM HOON SIK; LEE BYUNG GWON; LEE SANG DEUK; KWON YOUNG SOO; LEE HYUN JOO
    权利人:KOREA INST SCI & TECH
    摘要:A catalyst of the formula (1) for the synthesis of alkylene carbonate by reacting alkylene oxide and carbon dioxide n n n L m MX n   (1) n n n wherein L is selected from a group of pyridines; n M is a metal atom selected from Zn, Fe, Mn, Pb and In; n X is a halogen atom selected from Cl, Br and I; n m is 1 or 2, and n n is 2 or 3.

    专利号:WO-2023112055-A1
    优先权日:2021-12-15
    标 题 :New synthetic process design for the synthesis of carboxy tormifene and purity analysis to strengthen antidoping testing
    发明人:KUMAR GANGASANI JAGADEESH; PAWAR SACHIN DATTRAM; RADHAKRISHNANAND PULLAPANTHULA; MURTY UPADHYAYULA SURYANARAYANA; SAHU PURAN LAL; DUBEY SACHIN; SAHU KAPENDRA; UPADHYAY AWANISH; KUMAR PRAMOD
    权利人:DIRECTOR NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RES GUWAHATI NIPER G; DIRECTOR NAT DOPE TESTING LABORATORY NDTL
    摘要:The present invention relates to a process for preparing a compound of formula I: I. The compound of formula I is useful in anti-doping tests.

    专利号:US-6407264-B2
    优先权日:2000-02-11
    标 题:Synthesis of alkylene carbonates using a catalyst system comprising metal halide and pyridine or pyridine derivative
    发明人:KIM HOON SIK; KIM JAI JUN; LEE BYUNG GWON; KIM HONG GON
    权利人:KOREA INST SCI & TECH
    摘要:The present invention relates to a method to prepare alkylene carbonate of the formula (1) n wherein, R 1 and R 2 are each independently H; C 1 -C 4 alkyl or phenyl group; n which method characterized by reacting alkylene oxide with carbon dioxide in the presence of a catalyst system comprising a) metal halide [MX m ] and b) pyridine or pyridine derivative [Py], wherein Py is selected from a group of pyridines; M is a metal atom selected from the group consisting of Zn, Fe, Mn, Pb and In; X is a halogen selected from the group consisting of Cl, Br and I; and m is 2 or 3.

    专利号:WO-2011000481-A1
    优先权日:2009-07-02
    标 题 :Synthesis of pyrazine derivates
    发明人:IGNATYEV NIKOLAI MYKOLA; SHEREMETEV ALEXEI B; ALEXANDROVA NATALIA S
    权利人:MERCK PATENT GMBH; IGNATYEV NIKOLAI MYKOLA; SHEREMETEV ALEXEI B; ALEXANDROVA NATALIA S
    摘要:The present invention relates to a method for producing pyrazine derivates, wherein the reaction medium comprises at least one ionic liquid, and to the use of ionic liquids for producing pyrazine derivates.
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    合成参考文献


    摘要:Kalyani, D.; Desai, L. V., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 758.
    摘要:Molander, G. A.; Ryu, D., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 2, 35.
    摘要:D. J. Brown and X. R. Mihm. J. Am. Chem. Soc. 77, 1723 (1955).
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