CAS: 586-35-6; 2-Bromoterephthalic Acid

该化合物是磷酸的一种溴化衍生物,其特点是在芳香环的2位置上存在一种溴替代物,该化合物是有机合成的多用途中间体,特别是在准备功能化聚合物,金属-有机框架和制药建筑构件方面.其溴毒性可增强反应性,使铃木或Heck等选择性的交叉反应能够相互交织.

结构式图片

相似化合物

58123-69-6 89891-70-3 89891-69-0

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号553-94-6 2,5-二甲基溴苯 | CAS号90001-43-7 2-溴对苯二甲醛 | CAS号871876-77-6 2-bromo-1,4-bis... | CAS号99-94-5 对甲基苯甲酸 | CAS号108-95-2 苯酚 | CAS号7697-26-9 3-溴-4-甲基苯甲酸 | CAS号10312-55-7 2-氨基对苯二甲酸 | CAS号18870-13-8 2,5-dicyanobrom... | CAS号7664-93-9 硫酸 | CAS号214621-81-5 9-[2,5-bis(chlo... | CAS号25539-20-2 2-苯氧基对苯二甲酸 | CAS号30240-01-8 1,4-Benzenedica... | CAS号6342-72-9 2-羟基对苯二甲酸二甲酯 | CAS号636-94-2 2-羟基对苯二甲酸 | CAS号10035-10-6 氢溴酸 | CAS号311768-09-9 2-[2,5-bis(chlo... | CAS号13815-89-9 1,4-BENZENEDICA... | CAS号18643-86-2 二甲基溴对苯二酸酯 | CAS号1186377-08-1 2.5-二羧基苯硼酸频哪醇酯

合成工艺路线路线简述

  • 89980-92-7 = 586-35-6 + 91760-66-6
    反应条件:1.1 Reagents: Potassium Peroxymonosulfate Sulfate (2Khso5.Khso4.K2So4) Catalysts: 3,5-Bis(1,1-Dimethylethyl)-2-Iodobenzoic Acid; 26 H,Rt
    标题:Mechanochemical Catalytic Oxidations In The Solid State With In Situ-Generated Modified Ibx From 3,5-Di-Tert-Butyl-2-Iodobenzoic Acid (Dtb-Ia)/oxone
    作者:Mishra,Abhaya Kumar; Moorthy,Jarugu Narasimha
    参考文献:Organic Chemistry Frontiers 日期:2017 卷标:4(3) 页码:343-349
Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于溴,Sodium Bromide体系中,化学反应生成 2-溴四苯醌
参考文献:Whitmore; Isenhour,Journal Of The American Chemical Society,1929,Vol. 51,P. 2786
标题:Whitmore; Isenhour,Journal Of The American Chemical Society,1929,Vol. 51,P. 2786

海关参考信息

专利信息


专利号:US-7880026-B2
优先权日:2006-04-14
标 题 :MOF synthesis method
发明人:NI ZHENG; MASEL RICHARD I
权利人:UNIV ILLINOIS
摘要:A rapid, simple and versatile metal organic framework molecule (MOF) synthesis method particularly adapted to make non-linear MOFs includes heating MOF precursors, such as a metal or metal oxide and an organic ligand, in a microwave oven for a period sufficient to achieve crystallization. Microwave-assisted MOF synthesis yields high quality MOF crystals in a reaction time ranging from about 5 seconds to about 2.5 minutes, compared to hours and days required in conventional solvothermal and hydrothermal methods. In addition, microwave assisted methods provide MOF materials with uniform crystal size and well-defined shape. Further, microwave synthesis of MOFs allows the size and shape of MOF crystals to be tailored for use in a wide range applications by manipulating reaction conditions. Secondary growth processes may also be employed to grow larger crystals using seeds obtained from microwave-assisted synthesis methods.

专利号:US-11739112-B2
优先权日:2017-02-02
标 题:Low temperature process for the synthesis of MOF carboxylate nanoparticles
发明人:PANCHAL MONIK; NOUAR FARID; SERRE CHRISTIAN; BENZAQUI MARVIN; SENE SAAD; STEUNOU NATHALIE; GIMÉNEZ MARQUÉS MONICA
权利人:CENTRE NAT RECH SCIENT; UNIV DE VERSAILLES—SAINT QUENTIN EN YVELINES
摘要:The present invention relates to low temperature process for preparing nanoparticles of porous crystalline Fe-, Al- or Ti-based MOF carboxylate materials with low polydispersity index, and uses thereof, particularly as catalyst support for carrying out heterogeneously catalyzed chemical reactions, or as gas storage/separation/purification material, or as matrix for encapsulating active principles (medicine, cosmetics).

专利号:US-9304126-B2
优先权日:2012-08-21
标题:Haptens of quetiapine
发明人:DONAHUE MATTHEW GARRETT; GONG YONG; SALTER RHYS; HRYHORENKO ERIC; DECORY THOMAS R; REMMERIE BART; SANKARAN BANUMATHI
权利人:JANSSEN PHARMACEUTICA NV; ORTHO CLINICAL DIAGNOSTICS INC
摘要:The invention relates to compounds of Formula I, wherein R 1 , R 2 , and R 3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from quetiapine. The invention also relates to conjugates of a quetiapine hapten and a protein.

专利号:US-8373005-B2
优先权日:2006-12-21
标题:Process for the synthesis of ethers of aromatic acids
发明人:RITTER JOACHIM C
权利人:DU PONT; RITTER JOACHIM C
摘要:Ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a copper (I) or copper (II) source and a diamine ligand that coordinates to copper.

专利号:US-2010056750-A1
优先权日:2006-12-21
标题:Process for the synthesis of halogenated aromatic diacids
发明人:RITTER JOACHIM C
权利人:RITTER JOACHIM C
摘要:The production of high-purity halogenated aromatic diacids from halogenated dimethylbenzene by oxidation with an oxygen-containing gas is conducted using a four-component catalyst system and a two-stage temperature process.

专利号:WO-2020248279-A1
优先权日:2019-06-14
标 题 :Continuous synthesis method for substituted benzoate organic matter
发明人:HONG HAO; LU JIANGPING; ZHANG ENXUAN; LIU ZHIQING; LI CHAO
权利人:JINLIN ASYMCHEM LABORATORIES CO LTD
摘要:The present invention provides a continuous synthesis method for a substituted benzoate organic matter. The continuous synthesis method comprises: in the presence of a catalyst and an organic solvent, continuously feeding an organic matter as represented by formula (I) and oxygen into a continuous reaction device for continuous oxidation reaction to obtain a substituted benzoate organic matter, and performing continuous discharge, wherein the substituted benzoate organic matter has a structure as represented by formula (II). Oxygen is a green reagent, and is cheap and easy to obtain; the present invention would not produce a large amount of waste gas, waste water, and waste residues after the completion of reaction, and the system is easy to handle. The use of continuous reaction operation can reduce the risk of solvent flash evaporation explosion due to high concentration oxygen in batch reactions. Under the same oxidation conditions, the use of a continuous preparation process can reduce the escape of oxygen, greatly increase the utilization of oxygen, simplify the operation, and improve the reaction safety and the yield of substituted benzoate organic matters.
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合成参考文献


参考文献:10.1055/s-0039-1691093
摘要:Synthesis of Tulrampator. Synfacts. 2019 Nov 18;15(12):1351. doi: 10.1055/s-0039-1691093.
参考文献:10.1007/978-3-030-43350-5_69
摘要:Ha TY, Ahn Y, Seo B, Cho D, Chang J. Characterizations of Nanocomposites of Liquid Crystalline Polymers. 2020. In: Polymers and Polymeric Composites: A Reference Series.
参考文献:10.1055/s-0041-1737649
摘要:Expanding the E3 Ligase Toolbox by Co-opting Methyl Readers. Synfacts. 2022 Jun 15;18(07):0801. doi: 10.1055/s-0041-1737649.
参考文献:10.1007/s11172-023-3826-8
摘要:Burlak PV, Kovalenko KA, Fedin VP. Preparation of heterogeneous catalysts by the post-synthetic modification of mesoporous metal-organic framework MIL-101. Russ Chem Bull. 2023 Mar;72(3):624–34. doi: 10.1007/s11172-023-3826-8.
参考文献:10.1038/s44160-024-00585-7
摘要:Liu S, Wang Y, Lyu KF, Lan X, Wang T. A one-pot strategy for anchoring single Pt atoms in MOFs with diverse coordination environments. Nat. Synth. 2024 Jun 20;3(9):1158–67. doi: 10.1038/s44160-024-00585-7.
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