CAS: 40928-13-0; 7-Chloro-1H-Benzo[d][1,3]Oxazine-2,4-Dione

该化合物是有机化合物,其特征为碘化物功能组和芳香环上的替代物,它来自异硫酸,以反应作用著称,特别是电磁反应,使其在有机合成中有用.该氯组的存在增强了其电子生殖特性,允许其参与各种化学转化.一般而言,该化合物是有机溶剂中的固体和溶解物.其应用包括作为制药,农用化学品和染料合成的中间体.安全考虑对于处理该化合物十分重要,因为它可能造成皮肤和呼吸刺激等风险.应当遵循适当的储存和处理程序,以减轻与其使用有关的任何危险.

英文名称7-Chloro-1H-Benzo[d][1,3]Oxazine-2,4-Dione
中文名称4-氯靛红酸酐
IUPAC名称7-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione
其它别名7-氯-1H-3,1-苯并恶嗪-2,4-二酮; 4氯靛红酸酐; 7-Chloro-2H-3,1-Benzoxazine-2,4(1H)-Dione
CAS编号40928-13-0
MFCD编号:MFCD00090431
EINECS号:624-747-2
分子式:C8H4ClNO3
分子量:197.57
产品CID: 1423676
产品分类有机原料→分子砌块→芳杂环类化合物→其它芳杂环类化合物

相似结构搜索
InChIKey: QRUPDIJQZCABTC-UHFFFAOYSA-N
InChI=1S/C8H4ClNO3/c9-4-1-2-5-6(3-4)10-8(12)13-7(5)11/h1-3H,(H,10,12)…
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数0.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别急性毒性类别4(经口)
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
严重眼刺激类别2A
警示词Warning(警告)
危险描述H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
危险等级IRRITANT
UN编号NONH for all modes of transport
危险品标志Xn
安全声明26-36/37
危险类别码22-36/37/38
WGK Germany3

欧盟法规

ECHA物质C&L通报

上下游产品

合成工艺路线路线简述

2-(((Benzyloxy)Carbonyl)Amino)-4-Chlorobenzoic Acid置于phosphorus Tribromide体系中,用乙醚作为反应溶剂,化学反应生成 4-氯靛红酸酐
参考文献:Quinazoline Derivatives,Compositions Thereof And Their Use In Treating
标题:Quinazoline Derivatives,Compositions Thereof And Their Use In Treating
摘要:本发明涉及具有以下通式的化合物:##str1## 其中r.Sup.1和r.Sup.2各自为氢,卤素,低级烷氧基或卤代(低级)烷基,R.Sup.3为二卤代苯基,萘基(低级)烷基,苯基(低级)烷基(其上有一个或两个由卤素,低级烷氧基,卤代(低级)烷基和低级烷基组成的基团取代)或噻吩基(低级)烷基,R.Sup.4为羧基或保护的羧基,Y为羰基,硫羰基或磺酰基,Z为低级亚烷基,以及其药学上可接受的盐,用于治疗糖尿病并发症.

海关参考信息

2903919090-氯苯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-6187923-B1
优先权日:1998-11-09
标题 :Process for the synthesis of quinazolinones
发明人：DENER JEFFREY MARK; LY CUONG QUOC
权利人:AXYS ADVANCED TECHNOLOGIES INC
摘要:The present invention provides a process for synthesizing a compound or a library of compounds of Formula 1A and 1B:

专利号:US-11440892-B2
优先权日:2019-07-03
标题 :Substituted dihydrobenzoxazinones, dihydroquinolones, and methods of their use and synthesis
发明人：SCHEIDT KARL A; LEE ANSOO
权利人:UNIV NORTHWESTERN
摘要:Disclosed are dihydrobenzoxazinone compounds, dihydroquinolone compounds, and methods of their synthesis. The disclosed compounds may be prepared by reacting a benzoxazinedione compound and a ketone compound in the presence of an N-heterocyclic carbine (NHC) catalyst to perform a NHC-catalyzed decarboxylative cycloaddition. The disclosed compounds may be utilized to treat diseases and disorders associated with the biological activity of dihydrobenzoxazinone compounds and dihydroquinolone compounds.

专利号:WO-0027831-A1
优先权日:1998-11-09
标题 :Process for the synthesis of quinazolinones

专利号:US-2021024473-A1
优先权日:2019-07-03
标题 :Substituted dihydrobenzoxazinones, dihydroquinolones, and methods of their use and synthesis