CAS: 37529-27-4; 4-Heptylaniline

上下游产品

庚基苯 Heptylbenzene 1078-71-3
7-(4-Nitrophenyl)Heptane 192934-88-6

📜4-硝基苯酚三氟甲基磺酸酯置于2-双环己基膦-2',6'-二甲氧基联苯,Potassium Phosphate Monohydrate,Palladium On Activated Charcoal,氢气,Palladium Diacetate体系中,用 乙醇,甲苯 作为反应溶剂,化学反应生成 4-庚基苯胺
参考文献:Design And Synthesis Of Boronic Acid Inhibitors Of Endothelial Lipase
标题:Design And Synthesis Of Boronic Acid Inhibitors Of Endothelial Lipase
摘要:Endothelial Lipase (El) And Lipoprotein Lipase (Lpl) Are Homologous Lipases That Act On Plasma Lipoproteins. El Is Predominantly A Phospholipase And Appears To Be A Key Regulator Of Plasma Hdl-C. Lpl Is Mainly A Triglyceride Lipase Regulating (V)Ldl Levels. The Existing Biological Data Indicate That Inhibitors Selective For El Over Lpl Should Have Anti-Atherogenic Activity,Mainly Through Increasing Plasma Hdl-C Levels. We Report Here The Synthesis Of Alkyl,Aryl,Or Acyl-Substituted Phenylboronic Acids That Inhibit El. Many Of The Inhibitors Evaluated Proved To Be Nearly Equally Potent Against Both El And Lpl,But Several Exhibited Moderate To Good Selectivity For El. (C) 2011 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2011.12.043