专利号:US-7169894-B2 优先权日:2001-11-14 标题 :Methods and compositions for reverse translation 发明人:MARTIN MARK T 权利人:MIRARI BIOSCIENCES INC 摘要:A process is disclosed by which a polynucleotide is directly synthesized from the peptide or protein that it encodes without the need for sequencing (or sequence analysis) of the peptide or protein. Information contained in the sequence of the peptide or protein is directly coupled, by the process of reverse translation, to the synthesis of the polynucleotide. The usefulness of reverse translation is that it facilitates the amplification of information held in the amino acid sequence (the primary structure) of an unknown protein or peptide. Amplification is useful for, among other things, the identification and/or scientific investigation of the peptide or protein.
专利号:US-2022389374-A1 优先权日:2021-05-06 标题:Use of functionalized and non-functionalized ecms, ecm fragments, peptides and bioactive components to create cell adhesive 3d printed objects 发明人:KAUR AMAN; HERNANDEZ VICTOR; NSIAH BARBARA; ARIAS ISABEL; ALVAREZ LUIS 权利人:LUNG BIOTECHNOLOGY PBC 摘要:Embodiments of this disclosure relate to bioinks and bioink compositions. These bioinks may be 3D printed into a hydrogel. The printed hydrogel may support primary cell and induced pluripotent stem cell attachment, proliferation, and spreading. Compounds in the bioink may be modified to incorporate chemical functionality, such as by chemical synthesis means. Incorporating chemical functionality may allow the incorporation of modified material as a component in the bioink. The modifications may allow chemical conjugation of a desired component. The desired component may maintain its cell interactive feature to aid in cell attachment and proliferation. Such incorporation may allow modulation of the bioprinted object's mechanical properties without interfering with cell adhesion.
专利号:US-12234299-B2 优先权日:2018-11-22 标 题 :Peptides for inducing bacteriocin synthesis and methods to identify and/or select and/or optimize the same 发明人:MIGNOLET JOHANN; HOLS PASCAL; LEDESMA GARCÃ?A LAURA 权利人:SYNGULON S A; UNIV CATHOLIQUE LOUVAIN 摘要:Described herein is a peptide or peptidomimetic with a length of at least 6 residues comprising, consisting essentially of, or consisting of the sequence motif Xaa1-Trp-Xaa2-Xaa3-Xaa4-Xaa5 (SEQ ID NO:1), wherein: Xaa1 represents an aromatic residue (Phe, Tyr, Trp, His), Cys or Ser; Xaa2, Xaa3 and Xaa4 represent any residue; and Xaa5 represents Gly, lie or Val.
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合成参考文献
参考文献:10.1007/s11274-013-1368-3 摘要:Pandey N, Malik RK, Kaushik JK, Singroha G. Gassericin A: a circular bacteriocin produced by Lactic acid bacteria Lactobacillus gasseri. World Journal of Microbiology and Biotechnology. 2013 May 28;29(11):1977–87. doi: 10.1007/s11274-013-1368-3.