CAS: 18368-76-8; 2-Chloro 3-Methylpyridine

相似化合物

58584-94-4 72093-12-0 59782-88-6

上下游产品

CAS号1003-73-2 3-甲基吡啶-N-氧化物 | CAS号75-44-5 光气 | CAS号1003-56-1 2-羟基-3-甲基吡啶 | CAS号824-72-6 苯膦酰二氯 | CAS号108-99-6 3-甲基吡啶 | CAS号78948-09-1 acetyl hypofluorite | CAS号109-09-1 2-氯吡啶 | CAS号74-88-4 碘甲烷 | CAS号67-66-3 氯仿 | CAS号111108-72-6 3-(溴甲基)-2-氯吡啶 | CAS号58584-94-4 2,6-二氯-3-甲基吡啶 | CAS号132097-09-7 2,4-二氯-3-甲基吡啶 | CAS号104396-10-3 1-(3-甲基-吡啶-2-基)-哌嗪 | CAS号10273-90-2 3-甲基-2-苯基吡啶 | CAS号2942-59-8 2-氯烟酸 | CAS号1603-40-3 2-氨基-3-甲基吡啶 | CAS号6654-69-9 3-methyl-N-(3-m... | CAS号20970-75-6 2-氰基-3-甲基吡啶 | CAS号72093-14-2 2-氯-3,6-二甲基吡啶

3-甲基-2-吡啶甲酸置于次氯酸叔丁酯,二氯甲烷,碳酸氢钠体系中,化学反应 20.0H,以80%的收率获得2-氯-3-甲基吡啶
参考文献:在氧条件下用2-卤代甲烷对2-吡啶甲酸进行无过渡金属的脱羧卤化作用†
标题:在氧条件下用2-卤代甲烷对2-吡啶甲酸进行无过渡金属的脱羧卤化作用†
摘要:描述了一种方便有效的合成2-卤素取代的吡啶的方法.经由n-氯卡宾中间体使2-吡啶甲酸与二卤代甲烷的脱羧卤化反应顺利进行,以令人满意的收率在无过渡金属的条件下提供2-卤素取代的吡啶.这种新型的脱羧卤化反应操作简单,并且具有很高的官能团耐受性.
Doi:10.1039/c9Gc02407G

专利信息

专利号:US-8853410-B2
优先权日:2009-04-30
标 题:Process for preparing substituted isoxazoline compounds and their precursors
发明人：RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN
权利人:RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN; BASF SE
摘要:The present invention relates to a new method of preparing halogenated styrene compounds of formula (VIII) n nwhich are precursors in the process of synthesis of substituted isoxazoline compounds of formula (I)n n nwherein R 1 to R 5 , R 8 and R 9 are described as in the description.n n The present invention relates further to the synthesis of compounds of formula (I) starting from acetophenones. The desired styrenes of formula are prepared from the appropriate substituted acetophenone. Asides bromo anilines react with formoxime. Obtained oximes undergo a cycloaddition with the styrenes and give isoxazolines. Compounds of formula (I) can then be prepared in a palladium catalyzed carbonylative amination reaction of the isoxazolines.

专利号:CN-109096181-B
优先权日:2018-09-29
标题:A method for ultrasonic-assisted green synthesis of 2-sulfonylpyridine derivatives

专利号:EP-3929197-B1
优先权日:2015-08-12
标 题:Intermediates for the synthesis of microbiocidal heterobicyclic derivatives

专利号:US-8841306-B2
优先权日:2008-11-20
标 题:Antimicrobials
发明人：JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KANWAR SANDEEP; MAGADI SITARAM KUMAR; SHARMA SUDHIR KUMAR
权利人:JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KANWAR SANDEEP; MAGADI SITARAM KUMAR; SHARMA SUDHIR KUMAR; PANACEA BIOTEC LTD
摘要:The present invention relates to novel phenyl oxazolidinone compounds of formula I, their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of formula I or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of formula I and methods of using them. The compounds of the present invention are useful as antimicrobial agents, effective against a number of aerobic and/or anaerobic Gram positive and/or Gram negative pathogens such as multi drug resistant species of Staphylococcus, Streptococcus, Enterococcus, Bacterioides, Clostridia, H. influenza, Moraxella , acid-fast organisms such as Mycobacterium tuberculosis as well as Linezolid resistant species of Staphylococcus and Enterococcus.

专利号:CN-117603950-A
优先权日:2024-01-02
标 题:A nitrilase mutant and its application in catalytic synthesis of 2-chloronicotinic acid

专利号:CN-114196658-B
优先权日:2021-12-09
标题 :Nitrilase mutant and application thereof in catalytic synthesis of 2-chloronicotinic acid