CAS: 102608-53-7; 1-Hexadecen-2-Ol,3,7,11,15-Tetramethyl

专利信息

专利号:US-4125735-A
优先权日:1975-03-20
标 题 :Synthesis of esters of acetylenic alcohols
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of perfume products, Vitamin E and intermediates described herein involving a coupling reaction. For instance, a process for the synthesis of dehydrophytol and Vitamin E comprising forming a C15 acetylene from hexahydropseudoionone and then coupling said acetylene with 1-acetoxy-4-chloro-3-methylbut-2-ene to form a C20 acetoxy-enyne. The latter is readily subjected to partial hydrogenation and saponification in that order to form a dehydrophytol, a useful intermediate for the synthesis of Vitamin E and other products.

专利号:US-4039591-A
优先权日:1975-03-20
标 题:Synthesis of dehydrophytol and Vitamin E
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of dehydrophytol and Vitamin E comprising forming a C15 acetylene from hexahydropseudoionone and then coupling said acetylene with 1-acetoxy-4-chloro-3-methylbut-2-ene to form a C20 acetoxy-enyne. The latter is readily subjected to partial hydrogenation and saponification in that order to form a dehydrophytol, a useful intermediate for the synthesis of Vitamin E and other products.

专利号:US-4115466-A
优先权日:1975-10-16
标题:Synthesis of acetylenic compounds useful in preparing dehydrophytols and Vitamin E
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of an acetylenic hydrocarbon from an acetylenic carbinol which involves first replacing the hydroxyl group of the carbinol with a halogen to form a propargylic halide, dehalogenating the propargylic halide to form an allene, and isomerizing said allene to the desired acetylene. The present invention is particularly useful in the synthesis of Vitamin E.

专利号:US-5231232-A
优先权日:1991-12-18
标题 :Method of preparing C-18 ketones used in the manufacture of Vitamins E and K
发明人：BABLER JAMES H
权利人:UNIV LOYOLA CHICAGO
摘要:Methods of forming unsaturated C-18 ketones which can be used in the synthesis of Vitamins E and K 1 are disclosed. One procedure involves coupling a C-9 primary allylic halide to a carbonyl-group-containing C-9 terminal alkyne. A second, two-step procedure employs a C-4 bis allylic halide (molar excess) and a carbonyl-group-containing C-9 terminal alkyne to form a C-13 primary allylic halide. The C-13 primary allylic halide can then be converted to the desired C-18 ketone by reaction with 2-methyl-3-butyn-2-ol. Novel C-18 ketones (e.g., 14-hydroxy-6,14-dimethyl-10-methylene-5-pentadecen-7,12-diyn-2-one), C-13 allylic halides (e.g., 10-chloromethyl-6-methyl-5,10-undecadien-7-yn-2-one) and C-9 allylic halides (e.g., 6-chloromethyl-2-methyl-6-hepten-3-yn-2-ol) are formed in the process.

专利号:US-2010240923-A1
优先权日:2007-11-29
标题:Enzymatic synthesis of (meth)acrylic esters of hydroxy-functional aromas
发明人：HAERING DIETMAR; WINTER GABI; SCHNELLER ARNOLD; AULENTA FRANCESCA
权利人:BASF SE
摘要:A process for preparing (meth)acrylic esters (F) of hydroxy-functional aromas (A), in which at least one hydroxy-functional aroma (A) in the presence of at least one enzyme (E) is esterified with (meth)acrylic acid (S), or transesterified with at least one (meth)acrylic ester (D), the reaction in the case of the transesterification being effected in the absence of solvents.

专利号:US-4072725-A
优先权日:1975-10-16
标题 :Dehydrophytol
发明人：CLOSE RALPH E; OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A process for the synthesis of dehydrophytol and Vitamin E comprising forming a C15 acetylene from hexahydropseudoionone and then coupling said acetylene with 1-acetoxy-4-chloro-3-methylbut-2-ene to form a C20 acetoxy-enyne. The latter is readily subjected to partial hydrogenation and saponification in that order to form a dehydrophytol, a useful intermediate for the synthesis of Vitamin E and other products.