CAS: 86811-58-7; Fluazuron

该化合物是一种合成化学化合物,被归类为昆虫生长调节器,主要用于农业和兽医用途;它属于苯甲醚和功能类别,干扰昆虫的青金合成,从而抑制昆虫的生长和发育;这一机制使它能够有效防治各种虫害,特别是控制虱子和其他雌性寄生虫;氟甲通常用于配方,允许有针对性地交付,最大限度地减少对非目标生物的影响;该化合物的特点是它对哺乳动物和鸟类的毒性相对较低,从而在综合虫害管理战略中成为首选选择;此外,该化合物具有中度的环境持久性,需要认真考虑应用率和时机,以减轻潜在的生态影响;其功效和安全性已导致其在农业环境以及兽医医学中的使用,特别是在牲畜管理方面;与任何农药一样,在使用氟甲氨时,遵守管制准则和安全议定书至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

3-氯-2-(2-氯-5-氨基-苯氧基)-5-三氟甲氧基吡啶 4-Chloro 3-(3Chloro-5-Trifluoromethylpyridin-2-Yloxy)Aniline 87170-48-7

合成工艺路线路线简述

    2,6-二氟苯甲酰胺置于n-氯代丁二酰亚胺,Potassium Carbonate体系中,用 二甲基亚砜,甲苯 作为反应溶剂,化学反应 58.0H,反应生成 啶蜱脲
    参考文献:一种吡虫隆的制备方法
    标题:一种吡虫隆的制备方法
    摘要:本发明公开了一种吡虫隆的制备方法,本发明所述的方法以2,6‑二氟苯甲酰胺为起始物合成得到吡虫隆.本发明为吡虫隆的生产提供了一种新的工艺新的选择,避免了因为原材料的供应问题而影响到吡虫隆的生产,同时,新方法的生产成本较老工艺有所降低,在市场竞争中优势明显.

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:EP-1306084-B1
    优先权日:1998-06-09
    标 题 :Compositions for the control of parasitic infestations in fish
    发明人:ALEXANDER SVEIN; EVENSEN OYSTEIN; SYVERTSEN CHRISTIAN; MARTINSEN BERNT
    权利人:PHARMAQ AS
    摘要:Injectable compositions comprising antiparasitically active chitin synthesis inhibitor substances are described, for controlling parasitic infestations including infestations with sea lice and isopod species in farmed fish. The compositions are optionally formulated in a fish vaccine. The antiparasitically active chitin synthesis inhibitor substances protect the fish against parasites for a substantial period of time after injection. Useful embodiments include compositions with lufenuron that confer protection against new parasitic infestation for an extended period of time after treatment.

    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    专利号:WO-2021074311-A1
    优先权日:2019-10-16
    标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)

    专利号:US-11369113-B2
    优先权日:2017-10-27
    标题:Vector control compositions, methods and products utilizing same
    发明人:HUETER OTTMAR FRANZ; HOPPE MARK; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; FEDOU NICOLAS; GODINEAU EDOUARD; WEGE PHILIP; MAIENFISCH PETER
    权利人:SYNGENTA PARTICIPATIONS AG
    摘要:The present inventions concerns use of a specific methoxyacrylate compound to control mosquitoes, and vector control products comprising that methoxyacrylate compound, in particular the invention relates to a substrate, to a composition, for controlling mosquitoes, and to a specific methoxyacrylate compound, processes for the synthesis of mosquitocidal methoxyacrylate compounds and new intermediates.
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    主要参考文献


    1: Morel N, Signorini ML, Mangold AJ, Guglielmone AA, Nava S. Strategic control of Rhipicephalus (Boophilus) microplus infestation on beef cattle grazed in Panicum maximum grasses in a subtropical semi-arid region of Argentina. Prev Vet Med. 2017 Sep 1;144:179-183. doi: 10.1016/j.prevetmed.2017.06.006. Epub 2017 Jun 15. doi: 10.1016/j.parint.2017.05.005. Epub 2017 May 17. doi: 10.1016/j.parint.2017.04.006. Epub 2017 Apr 20. doi: 10.1016/j.chemosphere.2017.01.069. Epub 2017 Jan 12. doi: 10.1016/j.prevetmed.2016.10.019. Epub 2016 Nov 3. doi: 10.1111/cbdd.12872. Epub 2016 Nov 2. doi: 10.1590/S1984-29612016006. Epub 2016 Mar 11. doi: 10.1093/jme/tjv129. Epub 2015 Aug 19. doi: 10.1016/j.exppara.2015.02.004. Epub 2015 Feb 26. doi: 10.1016/j.vetpar.2015.01.015. Epub 2015 Jan 28. doi: 10.1016/j.rvsc.2014.04.012. Epub 2014 May 5. doi: 10.1016/j.vetpar.2014.01.012. Epub 2014 Jan 29. doi: 10.1016/j.actatropica.2014.01.008. Epub 2014 Feb 4. doi: 10.1016/j.foodchem.2013.08.027. Epub 2013 Aug 14. doi: 10.1002/jemt.22282. Epub 2013 Sep 2. doi: 10.1007/s00436-013-3282-x. doi: 10.1007/s00436-012-3103-7. Epub 2012 Sep 20. doi: 10.1016/j.exppara.2012.02.023. Epub 2012 Mar 21. doi: 10.1186/1756-3305-5-40.
    20: Davis RM, Cleugh E, Smith RT, Fritz CL. Use of a chitin synthesis inhibitor to control fleas on wild rodents important in the maintenance of plague, Yersinia pestis, in California. J Vector Ecol. 2008 Dec;33(2):278-84.

    合成参考文献


    参考文献:10.1007/s00436-021-07235-3
    摘要:Hüe T, Berger A, Wang HH, Grant WE, Teel PD, de León AAP. Integrated control of the cattle tick, Rhipicephalus australis (Acari: Ixodidae), in New Caledonia through the Pasture and Cattle Management method. Parasitol Res. 2021 Aug;120(8):2749–58. doi: 10.1007/s00436-021-07235-3.
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