专利号:US-8071330-B2 优先权日:2004-12-27 标题:Process for the synthesis of cefaclor 发明人:MOODY HAROLD MONRO; DOOREN THEODORUS JOHANNES GODFRIED MARIA VAN 权利人:MOODY HAROLD MONRO; DOOREN THEODORUS JOHANNES GODFRIED MARIA VAN; DSM IP ASSETS BV 摘要:The present invention relates to a process for the synthesis of cefaclor, which process comprises reacting 7-amino-3-chloro cephalosporanic acid (7-ACCA) with D-phenylglycine in activated form (PGa) in the presence of an enzyme in a reaction mixture to form cefaclor, wherein at least part of 7-ACCA and/or PGa are added to the reaction mixture during the course of the reaction. The invention also relates to an aqueous mixture comprising an amount of cefaclor of >10 (w/w) %, an amount of 7-amino-3-chloro cephalosporanic acid of <2 (w/w) %, and an amount of D-phenyl glycine of <2 (w/w) % and a process for the recovery of cefaclor from this aqueous mixture. The invention also relates to cefaclor in crystal form having an absorbance at 400 nm (A 400 ) of less than 0.250.
专利号:US-9815809-B2 优先权日:2013-07-05 标题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols 发明人:LETINOIS ULLA; NETSCHER THOMAS 权利人:DSM IP ASSETS BV 摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.
专利号:US-6096853-A 优先权日:1998-12-21 标 题 :Synthesis of phenolic monomers containing imide or diimide moieties and high heat carbonate polymers prepared therefrom 发明人:AMERIK VALENTINA; HOEKS THEODORUS L; LIKIBI PARFAIT JEAN MARIE; NELSON MARK 权利人:GEN ELECTRIC 摘要:A process has been surprisingly discovered that can produce a high heat carbonate polymer (i.e., one with a Tg greater that 150° C.), without the drawbacks encountered in attempts to produce a high heat carbonate polymer. The process of the instant invention comprises the steps of: n (1) reacting an aromatic amine with a dihydric phenol to prepare an aminophenol; n (2) reacting an anhydride or dianhydride with the aminophenol to prepare a phenolic precursor; and n (3) reacting the phenolic precursor with a carbonate precursor to prepare a high heat carbonate polymer.
专利号:US-9803050-B2 优先权日:2014-10-08 标 题:Dispersant for use in synthesis of polyaryletherketones 发明人:NAIR KAMLESH P 权利人:TICONA LLC 摘要:A method for forming a polyaryletherketone is described. More particularly, a reaction mixture is initially supplied to the reactor vessel that contains one or more precursor monomers. A heteroaryl compound is also added to the reaction mixture. The reaction can be carried out according to, e.g., an electrophilic aromatic substitution reaction or a nucleophilic aromatic substitution reaction. The heteroaryl compound can serve as a dispersant to the polymer as it is formed. This minimizes the likelihood of gelling of the product polymer within the reactor vessel and limits the impact of process disruptions on the production of the polyaryletherketone.
专利号:US-6121495-A 优先权日:1995-09-12 标题:Ethynyl substituted aromatic compounds, synthesis, polymers and uses thereof 发明人:BABB DAVID A; SMITH JR DENNIS W; MARTIN STEVEN J; GODSCHALX JAMES P 权利人:DOW CHEMICAL CO 摘要:Compounds of ethynyl aromatic compounds form polymers which have high thermal stability. The monomers are useful for coating a wide variety of substances such as dielectric coatings where high thermal resistance is desirable including electronic components such as computer chips.
专利号:WO-2023113033-A1 优先权日:2021-12-16 标题 :Gas diffusion electrode 发明人:KONDO SHOICHI; MAEDA SHINICHI; SHIGA NORIHITO 权利人:NISSAN CHEMICAL CORP 摘要:[Problem] The present invention addresses the problem of increasing the rate of reaction by controlling ammonium ions, which are generated by ammonia as the objective of the electrolytic synthesis of ammonia and protons that are supplied to the cathode, by means of the cathode and the cathode catalyst layer. [Solution] The present invention provides a gas diffusion electrode which is integrated with a catalyst layer that uses a material selected from the group consisting of cathode catalyst layer materials. Examples of the cathode catalyst layer materials include a fired body and an ionic liquid.
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合成参考文献
参考文献:10.1002/chem.200902123 摘要:Basheer MC, Oka Y, Mathews M, Tamaoki N. A light-controlled molecular brake with complete ON-OFF rotation. Chemistry. 2010 Mar 15;16(11):3489–96. doi: 10.1002/chem.200902123.