CAS: 507-25-5; Periodomethane

该化合物是一种挥发性有机碘化合物,在有机合成过程中广泛用作甲基制剂,其高反应性和选择性使将甲基混合物引入酒精,氨和硫柳类等核素中具有价值; 甲氨酯在合成药品,农用化学品和精美化学品方面特别有用; 其低沸点(42.5°C)便于反应后清除,而其在水性条件下的稳定性则确保了持续性能; 然而,由于其毒性和潜在致癌性,适当的处理和储存至关重要; 氨酯通常用安培玻璃瓶供应,以尽量减少轻度降解.

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CAS号56-23-5 四氯化碳 | CAS号74-88-4 碘甲烷 | CAS号67-64-1 丙酮 | CAS号7681-11-0 碘化钾 | CAS号75-47-8 三碘甲烷 | CAS号75-03-6 碘乙烷 | CAS号76-06-2 氯化苦 | CAS号7784-23-8 碘化铝 | CAS号13517-10-7 三碘化硼 | CAS号861069-59-2 Triiodoacetonitrile | CAS号74-89-5 氨基甲烷 | CAS号34557-54-5 methane | CAS号143-33-9 氰化钠 | CAS号56-23-5 四氯化碳 | CAS号75-73-0 四氟化碳 | CAS号10049-16-8 氟化钒(IV) | CAS号10049-12-4 三氟钒 | CAS号676353-70-1 iodide pentafluoride | CAS号2314-97-8 三氟碘甲烷 | CAS号75-61-6 二溴二氟烷

合成工艺路线路线简述

    氯化苦置于乙醇,Potassium Iodide体系中,化学反应生成 四碘甲烷
    参考文献:Kretow; Melnikow,Zhurnal Obshchei Khimii,1932,Vol. 2,P. 202,206
    标题:Kretow; Melnikow,Zhurnal Obshchei Khimii,1932,Vol. 2,P. 202,206

    专利信息


    专利号:US-6730790-B2
    优先权日:2002-03-01
    标 题:Chlorinated heterocyclic compounds and methods of synthesis
    发明人:KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
    权利人:R T ALAMO VENTURES I LLC
    摘要:Compositions of the present invention comprise chlorinated heterocyclic compounds, including racemic monochloroflosequinan, purified enantiomers of monochloroflosequinan and the sulfone derivative of monochloroflosequinan. The methods of the present invention comprise the synthesis of racemic monochloroflosequinan and derivatives thereof, including the sulfone derivative. Intermediates in the synthesis are also provided. The methods further comprise the synthesis of enantiomers of monochloroflosequinan.

    专利号:US-9512250-B2
    优先权日:2012-02-23
    标 题 :Manganese catalyzed photopolymerization of fluorinated monomers
    发明人:ASANDEI ALEXANDRU D
    权利人:UNIV CONNECTICUT
    摘要:The disclosure discloses initiating systems for the radical polymerization of alkenes, and especially fluorine substituted alkenes. The polymerization is catalyzed by a metal carbonyl, preferably manganese carbonyl. The polymerization is initiated directly from alkyl halides at room temperature under visible white light. The polymers also allow the synthesis of block copolymers. The process comprises polymerizing at least one alkene monomer in the presence of a halide radical initiator, carbonyl catalyst and a solvent, under reaction conditions and for a time sufficient to polymerize the at least one alkene monomer to form a polymer. The present disclosure provides a method for living polymerization of alkene monomers which provides a high level of macromolecular control over the polymerization process and which leads to uniform and controllable polymeric products. This disclosure also provides a method for activating any halide (Cl, Br, I) chain ends of such polymers for the synthesis of block copolymerizations.

    专利号:US-7556789-B2
    优先权日:2003-05-14
    标 题:Low temperature synthesis of carbon nanotubes
    发明人:FAHLMAN BRADLEY D
    权利人:UNIV MICHIGAN CENTRAL
    摘要:This invention provides: 1 ) methods for the identification of broad spectrum holins with a high level of nonenzymatic activity in membranes; 2 ) conditions required for maintaining and increasing the anti-microbial and anti-pest efficacy of holins in gene fusions; 3 ) a method for effective targeting of holins expressed in plants through use of leader peptide to direct the holin protein in the plant apoplast and xylem; 4 ) methods for the control of bacterial and fungal diseases of plants and control of insect and nematode pests that attack plants by expression of gene fusion involving holins, C-terminal additions and leader peptides, and optionally, endolysis; 5 ) methods for increasing the shelf of cut flowers, and 6 ) transgenic plants useful for the production of novel antimicrobial proteins based upon holins.

    专利号:US-2012095211-A1
    优先权日:2010-09-22
    标 题 :Substituted proline inhibitors of hepatitis c virus replication
    发明人:BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D
    权利人:BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D; INTERMUNE INC
    摘要:The embodiments provide compounds of the general Formulae I, Ia, II, IIa, III, IIIa, IIIb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. The embodiments also provide methods for the synthesis of subject compounds and intermediates in the synthetic methods.

    专利号:US-4335100-A
    优先权日:1979-04-23
    标 题:Method of inhibiting dextransucrase and oral compositions for use therein
    发明人:ROBYT JOHN F; ZIKOPOULOS JOHN N
    权利人:UNIV IOWA STATE RES FOUND INC
    摘要:Dextransucrase synthesis of dextran from sucrose is inhibited by substituted sucrose compounds which have an inhibiting group bonded to the 5-position ring carbon. Oral compositions containing such substituted sucrose compounds can be used to control dextran formation in the mouth, and dextran comprises the principal component of dental plaque.

    专利号:US-3954585-A
    优先权日:1974-02-21
    标题 :Synthesis of trifluoromethyl-substituted compounds
    发明人:LAGOW RICHARD J; GERCHMAN LOIS L; JACOB ROBERT A
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:Trifluoromethyl-substituted compounds are formed in a corona discharge or glow discharge plasma of trifluoromethyl radicals from an organic trifluoromethyl source. A substrate possessing easily replaceable ligands such as halogen or carbonyl, is initially contacted either in the plasma and within a short distance from a downstream visible edge of the plasma or outside of the visible portion of the plasma and within a short distance from the downstream visible edge, to effect a substitution of the halogen or carbonyl ligand on the substrate with a trifluoromethyl radical without substantial decomposition of the substrate.
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    合成参考文献


    摘要:Ayad, T.; Pirat, J.-L.; Virieux, D., Science of Synthesis Knowledge Updates, (2022) 1, 321.
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#02298
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