CAS: 495-71-6; 1,4-Diphenylbutane-1,4-Dione

上下游产品

1,4-联苯基-1-丁酮 1,4-Diphenylbutan-1-One 5407-91-0
苯丁酮 Butyrophenone 495-40-9
4-氧代-4-苯基丁腈 4-Oxo-4-Phenylbutanenitrile 5343-98-6
苯丙酮 1-Phenyl-Propan-1-One 93-55-0
1-苯基-1,3-丁二酮 1-Phenylbutan-1,3-Dione 93-91-4
1-苯基-4-(三甲基硅烷基)-1-丁酮 γ-(Trimethylsilyl)Butyrophenone 17337-21-2
β-Iodopropiophenone 24070-51-7
4-Hydroxy-1,4-Diphenylbutan-1-One 107487-41-2
3-氯代苯丙酮 3-Chloropropiophenone 936-59-4
2-Bromo-1,4-Diphenyl-1,4-Butanedione 63104-99-4

Alpha-氯乙酰苯置于titanium(Iv) Isopropylate,乙基溴化镁体系中,用 四氢呋喃,乙醚,水 作为反应溶剂,化学反应 18.0H,以79%的收率获得产物1,2-联苯甲酰乙烷
参考文献:通过钛介导的 α-卤代酮还原均偶联合成 1,4-二酮
标题:通过钛介导的 α-卤代酮还原均偶联合成 1,4-二酮
摘要:1,4-二酮是通过 α-卤代酮的还原同偶联合成的.将格氏试剂添加到异丙醇钛 (Iv) 中会得到一种低价钛 (Iii) 中间体,据信该中间体可介导自由基二聚反应.该反应适用于各种芳族 α-卤代酮,包括杂芳族化合物.
DOI:10.1055/s-0037-1610245

专利信息

专利号:US-3929840-A
优先权日:1972-07-14
标题 :Labile esters of ({31 )(cis-1,2-epoxypropyl)phosphonic
发明人：CHRISTENSEN BURTON G; LEANZA WILLIAM J; ALBERS-SCHONBERG GEORG
权利人:MERCK & CO INC
摘要:Labile esters of (-)(cis-1,2-epoxypropyl)phosphonic acid are prepared from the free acid or salts thereof by reaction with an alcohol or a hydrocarbyl halide. In addition to their utility as intermediates in the synthesis of antibacterially active salts of (-)(cis-1,2-epoxypropyl)phosphonic acid, those esters have significant antibacterial activity.

专利号:US-2012295866-A1
优先权日:2011-04-13
标题:Synthesis And Use Of Glycoside Pro-Drug Analogs
发明人：SHULL BRIAN; BALDWIN JOHN; GOPALASWAMY RAMESH; HAROON ZISHAN
权利人:SHULL BRIAN; BALDWIN JOHN; GOPALASWAMY RAMESH; HAROON ZISHAN; NUTEK PHARMA LTD
摘要:The present invention relates to methods and compositions for the synthesis, production, and use of pro-drug analogs. This invention relates to a method for the production of a broad group of glycosylated drugs, including but not limited to propofol, acetaminophen, and camptothecin carbohydrate derivatives.

专利号:US-2012088915-A1
优先权日:2010-07-16
标 题 :Stereoselective methods, catalysts and intermediates for the synthesis of (-)-nutlin-3 and related compounds

专利号:US-2011263876-A1
优先权日:2008-09-19
标题:Expeditious synthesis of gibberllin a5 and esters thereof

专利号:EP-2350040-A1
优先权日:2008-09-19
标 题 :Expeditious synthesis of gibberllin a5 and esters thereof

专利号:CN-101580498-B
优先权日:2009-05-26
标 题:Green Synthesis of Polysubstituted Furans