CAS: 486-18-0; 3-Aethyl-12H-Indolo[2,3-A]Chinolizinium-Betain

专利信息

专利号:EP-0059817-B1
优先权日:1981-03-11
标 题 :Serpentine, alstonine and sempervirine drugs for the specific inhibition of tumurous and cancerous cells
摘要:1. Pharmaceutical compositions having preferential action on the replication of DNA and the synthesis RNA in tumorous, cancerous and viral cells, characterized in that they consist of microgranules having a neutral central core, at least one first intermediary layer comprising at least one alkaloid of the group of beta-carbolines of the type serpentine, alstonine, sempervirine and flavopereirine, and at least an outer layer made up by a microporous envelope, comprising at least a natural and/or synthetic polymer of the type : shellac, arabic gum, gelatine, cellulose, ethyl cellulose, cellulose acetophtalate, cellulose triacetate, polyvinyl pyrrolidone, polyoxyethylene glycol, methacrylates and styrene-acrylonitrile copolymers.