CAS: 4378-36-3; 2-(3-Methyl-2-Phenylmorpholin-4-yl)Ethyl 2-Phenylbutanoate
- ⚠️《2026年兴奋剂目录》
- 英文名称2-(3-Methyl-2-Phenylmorpholin-4-yl)Ethyl 2-Phenylbutanoate
- 中文名称芬布酯
- IUPAC名称2-(3-Methyl-2-phenylmorpholino)ethyl 2-phenylbutyrate
- CAS编号4378-36-3
- MFCD编号:MFCD00864478
- EINECS号:224-480-8
- FDA UNII编号:BKY8H56395
- 分子式:C23H29NO3分子量:367.48
- 产品CID: 1447266
- 同类组份化合物CAS6474-85-7 (HCl); 4378-36-3 (free base)
- 产品分类原料药 → 消化系统用药 → 食欲抑制药及其它减肥药
物理性质
- 沸点493.4 °C at 760mmHg
- 闪点252.2 °C
- 密度1.076 g/cm3
- PSA:38.77
- LogP:4.1233
- 折射率1.538
- 蒸汽压7.08E-10 mmHg at 25 °C
- 溶解性Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
- 外观形态淡黄色至极深橙色油状物至稠油状物
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用该化合物用于厌氧(食用抑制剂).
MSDS等安全信息
上下游产品
CAS号36854-57-6 2-苯基丁酰氯合成工艺路线路线简述
📜2-(3-甲基-2-苯基吗啉-4-基)-乙醇,Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于sodium Methylate体系中,化学反应生成 芬布酯
参考文献:Esters Of Phenyl Acetic Acids And A Process Of Making Same
标题:Esters Of Phenyl Acetic Acids And A Process Of Making Same
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905121000-正丙醇
2905130000-正丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8598153-B2
优先权日:2006-09-22
标题 :Method of treatment using fatty acid synthesis inhibitors
发明人：SINGH SHEO B; TOTA MICHAEL R; WANG JUN
权利人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN; MERCK SHARP & DOHME
摘要:The present invention relates to natural products that possess fatty acid synthesis inhibitor activity and can be used to treat and prevent diseases such as obesity, cancer, diabetes, fungal infections, Mycobacterium tuberculosis infections, malarial infections and other apicomplexan protozoal diseases.
专利号:WO-2005112945-A2
优先权日:2004-05-21
标题 :Synthesis of tetracyclines and analogues thereof
专利号:EP-1753713-A2
优先权日:2004-05-21
标 题 :Synthesis of tetracyclines and analogues thereof
专利号:CA-1250585-A
优先权日:1984-07-20
标题 :Process for controlled synthesis of the two diastereomeric forms of triazolyl-o,n-acetals
专利号:EP-1183385-A1
优先权日:1999-05-21
标题:Methods and materials for the synthesis of organic products
专利号:CA-2067959-A1
优先权日:1991-05-06
标题 :Squarylium compounds, and processes and intermediates for the synthesis of these compounds
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Krautscheid Y, Senning CJ, Sartori SB, Singewald N, Schuster D, Stuppner H. Pharmacophore modeling, virtual screening, and in vitro testing reveal haloperidol, eprazinone, and fenbutrazate as neurokinin receptors ligands. J Chem Inf Model. 2014 Jun 23;54(6):1747-57. doi: 10.1021/ci500106z. Epub 2014 Jun 12.
合成参考文献
摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
📝 需求与反馈
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