CAS: 31224-43-8; 3-Fluoropicolinaldehyde

相似化合物

152126-31-3 97509-75-6 31181-79-0

上下游产品

3-氟-2-甲基吡啶 3-Fluoro-2-Methylpyridine 15931-15-4

3-氟吡啶 反应生成3-氟吡啶-2-醛
参考文献:Imidazo-Pyrimidines And Triazolo-Pyrimidines: Benzodiazepine Receptor Ligands
标题:Imidazo-Pyrimidines And Triazolo-Pyrimidines: Benzodiazepine Receptor Ligands
摘要:提供了i式化合物,以及它们的制备方法.上述公式中的变量z1,Z2,Z3,R4,R5,R6,R7,R8和ar在此定义.这些化合物可以用于体内或体外调节gabaa受体的配体结合,并且在治疗人类,家养伴侣动物和家畜动物的各种中枢神经系统(cns)疾病方面特别有用.本文提供的化合物可以单独或与一种或多种其他cns药物联合使用,以增强其他cns药物的效果.还提供了用于治疗这些疾病的药物组合和方法,以及用于检测gabaa受体的配体的方法(例如,受体定位研究).

专利信息

专利号:US-2006025421-A1
优先权日:2004-06-25
标 题:Pyridyl piperazines for the treatment of CNS disorders
发明人：BRODNEY MICHAEL A
权利人:PFIZER
摘要:This invention is directed to compounds of Formula I and to pharmaceutical compositions comprising the compound of Formula I. n n where the dashed line represents an optional double bond; and where n is 1 or 2, and Ar 1 , Ar 2 , . . . and Z are as defined in the specification. The invention is also directed to a method of treating a disorder or condition that can be treated by altering serotonin-mediated neurotransmission, such as migraine, headache, cluster headache, anxiety, depression, etc. This invention is also directed to intermediates useful in the synthesis of compounds of Formula I.

专利号:CN-113603687-A
优先权日:2021-08-02
标 题:A new method for the synthesis of cyano-substituted imidazo[1,5-a]pyridines

专利号:US-12103929-B2
优先权日:2018-06-25
标题:Tricyclic compounds
发明人：FANG HAIQUAN; CHEN MINGMING; YANG GUIQUN; DU YUELEI; WANG YANPING; WU TONG; LI QINGLONG; ZHANG LEI; HU SHAOJING
权利人:JACOBIO PHARMACEUTICALS CO LTD
摘要:Disclosed are tricyclic compounds as bromodomain and extra-terminal (BET) inhibitors which are shown as formula I, their synthesis and their use for treating diseases. More particularly, disclosed are fused heterocyclic derivatives useful as inhibitors of BET, methods for producing such compounds and methods for treating diseases and conditions wherein inhibition of one or more BET bromodomains provides a benefit.

专利号:CN-111004171-A
优先权日:2019-12-18
标 题 :Novel synthesis method of 3-fluoropyridine-2-methanol