CAS: 18740-38-0; Thieno[2,3-D]Pyrimidine-2,4-Diol
该化合物是一种环状环状有机化合物,其特点是一个包括硫诺和火利度的合成物的引信环状系统;该化合物具有二元功能组,表明其结构中存在两个碳基(C=O)组;通常是晶状固体,显示极有机溶剂中中中溶性等特性;该铁环的存在有助于其独特的电子特性,影响其再活动及其与生物系统的相互作用;Thieno[2,3d]衍生物由于其潜在的生物活动,包括抗微生物和抗癌特性,对医药化学具有兴趣;该混合物的分子结构允许各种替代,从而进一步改变其药理学特征;与许多热循环一样,它可能参与各种化学反应,包括核分裂性替代和循环性,使其成为有机合成的灵敏化构件.应当与所有化学物质一样,由于潜在的毒性或再活性,遵守安全和处理预防措施.
- 英文名称Thieno[2,3-D]Pyrimidine-2,4-Diol
- 中文名称噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮
- IUPAC名称thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
- 其它别名2,4-18740-38-0二羟基噻吩[2,3-D]嘧啶; Thieno[2,3-D]Pyrimidine-2,4-Diol
- CAS编号18740-38-0
- MFCD编号:MFCD11520884
- EINECS号:808-604-3
- 分子式:C6H4N2O2S分子量:168.17
- 产品CID: 953324
- 产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物
相似化合物
2659313-22-9 2659313-19-4 2169589-51-7物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
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- 合成目标产物 2,4-Dihydroxythieno[2,3-D]Pyrimidine 主要起始原料 2-Amino-3-Cyanothiophene And Carbon Dioxide
- (文献来源)合成步骤主要原料 2-Amino-3-Cyanothiophene 和 Carbon Dioxide
📜2,4-二氯噻吩[2,3-D]嘧啶置于盐酸体系中,化学反应生成2,4-二羟基噻吩[2,3-D]嘧啶
参考文献:Robba,M. Et Al.,Bulletin De La Societe Chimique De France,1975,P. 587-591
标题:Robba,M. Et Al.,Bulletin De La Societe Chimique De France,1975,P. 587-591
海关参考信息
- 2905199090-其他饱和一元醇
2905590090-其他无环醇的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2006079916-A1
优先权日:2005-01-26
标 题 :Thieno [2,3-d] pyrimidine compounds as inhibitors of adp-mediated platelets aggregation
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
权利人:PHARMACIA & UPJOHN CO LLC; ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
专利号:US-4670560-A
优先权日:1986-04-28
标 题:Thienopyrimidine-2,4-dione derivatives and intermediates thereof
发明人：PRESS JEFFERY B; RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are generally vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.
专利号:US-4707550-A
优先权日:1986-04-28
标题 :N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas
发明人：PRESS JEFFERY B; RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are general vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.
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合成参考文献
参考文献:10.1007/s11030-008-9089-5
摘要:Heravi MM, Ranjbar L, Derikvand F, Alimadadi B. Three-component one-pot synthesis of 4,6-diarylpyrimidin- 2(1H)-ones under solvent-free conditions in the presence of sulfamic acid as a green and reusable catalyst. Mol Divers. 2008 Aug;12(3-4):191–6. doi: 10.1007/s11030-008-9089-5.
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