2-己酮置于palladium Dichloride 正丁基锂,二异丙胺体系中,用 四氢呋喃,正己烷,苯 用作溶剂,化学反应 0.5H,反应生成2-正丁基乙酰乙酸乙酯 参考文献:A New Efficient Homologation Reaction Of Ketones Via Their Lithiodiazoacetate Adducts 标题:A New Efficient Homologation Reaction Of Ketones Via Their Lithiodiazoacetate Adducts 摘要: Doi:10.1055/s-1983-30277
专利号:CN-114933532-A 优先权日:2022-05-13 标 题:A kind of method for continuous synthesis of 2-n-butyl acetoacetate in fixed bed
专利号:US-2009137557-A1 优先权日:2005-11-22 标题 :Calcilytic Compounds 发明人:KU THOMAS WEN FU; LIN HONG; LUENGO JUAN I; MARQUIS JR ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT; YAMASHITA DENNIS S 权利人:KU THOMAS WEN FU; LIN HONG; LUENGO JUAN I; MARQUIS JR ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT; YAMASHITA DENNIS S 摘要:Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.
专利号:US-2005113397-A1 优先权日:2002-01-31 标题:Imidazo[1,2-a]pyridine derivative 发明人:TAKEMURA MAKOTO; TAKAHASHI HISASHI; KAWAKAMI KATSUHIRO; TAKESHITA HIROSHI; KIMURA YOUICHI; WATANABE JUN; SUGIMOTO YUICHI; KITAMURA AKIHIRO; NAKAJIMA RYOHEI; KANAI KAZUO; FUJISAWA TETSUNORI 摘要:A compound reprsented by the following formula (I), its salts or nsolvates thereof capable of specifically or selectively expressig an antifungal activity in a broad spectrum based on the novel mechanism thereof of 1,6-β-glucan synthesis inhibition, and an antifungal agent containing any of them.
专利号:US-2007191395-A1 优先权日:2004-02-16 标题 :Heterocyclic compounds having antifungal activity 发明人:KAWAKAMI KATSUHIRO; KANAI KAZUO; FUJISAWA TETSUNORI; MORITA CHIKANORI; SUZUKI TAKASHI 权利人:KAWAKAMI KATSUHIRO; KANAI KAZUO; FUJISAWA TETSUNORI; MORITA CHIKANORI; SUZUKI TAKASHI 摘要:A compound which can specifically or selectively expresses an antifungal activity with a broad spectrum, based on the functional mechanism of 1,6-β-glucan synthesis inhibition, is provided, and an antifungal agent which comprises such a compound, a salt thereof or a solvate thereof is provided. A compound represented by the following formula (I), a salt thereof or a solvate thereof.
专利号:US-6287798-B1 优先权日:1996-05-01 标题 :Esculetin derivatives 发明人:JAMES ARTHUR; ARMSTRONG LYLE 权利人:IDG UK LTD 摘要:The invention concerns novel 6- or 7-substituted derivatives of esculetin (6,7-dihydroxy-2H-1-benzopyran-2-one), their synthesis, and their application as substrates for the detection of micro-organisms in samples where a derivative is enzymatically cleaved to release a colored or fluorogenic marker which has a low tendency to diffuse through agar or other aqueous environments.
专利号:CN-114920646-B 优先权日:2022-05-13 标题:A new synthesis method of 2-n-butylacetoacetate ethyl ester
摘要:Gnanaprakasam, B.; Chaudhari, M. B., Science of Synthesis Knowledge Updates, (2019) 2, 427. 摘要:P. Rumpf and R. Reynaud, C. R. Acad. Sci., Ser. C 250, 1501 (1960).