CAS: 100648-13-3; 6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzo[d]Imidazole
- 英文名称6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzo[d]Imidazole
- 中文名称三氯苯咪唑亚砜
- IUPAC名称6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-1H-benzo[d]imidazole
- 其它别名Triclabendazole Sulfoxide; 6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzimidazole; Triclabendazole Sulfoxide:6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzimidazole; 6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzo[d]Imidazole; Triclabendazole Sulfoxide Standard; Triclabendazole Ep Impurity A; 1H-Benzimidazole, 6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-
- CAS编号100648-13-3
- MFCD编号:MFCD19441813
- EINECS号:694-764-8
- FDA UNII编号:KY3O5E011U
- 分子式:C14H9Cl3N2O2S分子量:375.66
- 产品CID: 15340
- 产品分类化学试剂 → 有机试剂 → 砜,亚砜类化合物
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
triclabendazole合成工艺路线路线简述
📜三氯苯哒唑置于iron(III) Nitrate Nonahydrate,氧气,三氟乙酸体系中,用95 %的收率获得三氯苯达唑亚砜
参考文献:一种催化氧化硫醚制备亚砜化合物的方法
标题:一种催化氧化硫醚制备亚砜化合物的方法
摘要:本发明公开了一种新型催化氧化硫醚制备亚砜化合物的方法,所述方法通过催化剂和溶剂的筛选,在非常温和的条件下,有溶剂或无溶剂的条件下实现硫醚公斤级的氧化合成亚砜类化合物.本发明方法兼容烷基‑烷基,烷基‑芳基,芳基‑芳基硫醚及含硫杂环化合物.本发明制备方法具有广泛应用前景.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:2H-Benzimidazoles (Isobenzimidazoles). Part 7. A New Route To Triclabendazole [5-Chloro-6-(2,3-Dichlorophenoxy)-2-Methylthio-1H-Benzimidazole] And Congeneric Benzimidazoles作者:Brian Iddon,Peter Kutschy,Andrew G. Robinson,Hans Suschitzky,Walter Kramer,Franz A. Neugebauer
摘要:A New Synthesis Of The Selective Anthelmintic Agent Triclabendazole 7 From The Readily Available 5,6-Dichloro-2H-Benzimidazole-2-Spirocyclohexane 2 By Simple Steps Is Described. Analogous Benzimidazoles Difficult To Prepare By Conventional Methods Are Similarly Obtained. Triclabendazole Can Exist As A Low-Melting Metastable Solid (M.P. 85-90-Degrees-C) Convertible By Heating Or Recrystallisation From Ethanol Into Its Stable Form (M.P. 1 76-1 78-Degrees-C).
合成参考文献
摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
摘要:https://www.sciencedirect.com/science/article/abs/pii/S0003267018311693
📝 需求与反馈
尽可能描述清楚需求与问题信息
