CAS: 7148-06-3; N,N-Dimethylglycine Methyl Ester

该化合物是属于氨基酸衍生物类别的有机化合物,其特点是存在二甲基氨基氨基化合物和酯性功能组,有助于其化学反应和溶性.该化合物一般是无色的,可粉黄黄色,有温和的气味.该化合物溶于水和酒精等极地溶解剂,可用于各种化学应用.N,N-二甲基甘基甘基甲基酯经常用于生物化学研究,并可能用作合成药物和农用化学品的一个中间体,其生物意义与其在甲基化过程中的作用以及作为其他重要生物分子生物合成中的代谢前体有关.安全数据表明,与许多有机化合物一样,它应该谨慎处理,因为如果被摄取或吸入,它可能会对健康造成危害.

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合成工艺路线路线简述

    📜甜菜碱 反应生成 N,N-二甲基甘氨酸甲酯
    参考文献:Willstaetter,Chemische Berichte,1902,Vol. 35,P. 602
    标题:Willstaetter,Chemische Berichte,1902,Vol. 35,P. 602

    海关参考信息

    专利信息


    专利号:US-5827855-A
    优先权日:1992-12-28
    标题 :Hexahydronaphthalene ester derivatives their preparation and their therapeutic uses
    发明人:KOGEN HIROSHI; ISHIHARA SADAO; KOGA TEIICHIRO; KITAZAWA EIICHI; SERIZAWA NOBUFUSA; HAMANO KIYOSHI
    权利人:SANKYO CO
    摘要:Compounds of formula (I): (I) wherein R1 represents a group of formula (II) or (III): (II) (III) R2 is alkyl, alkenyl or alkynyl; R3 and R4 are each hydrogen, alkyl, alkenyl or alkynyl; R5 is hydrogen or a carboxy-protecting group; Ra is a group of formula -OR6; R6 is hydrogen; R6a and R6b are each hydrogen, a hydroxy-protecting group, alkyl, alkanesulfonyl, halogenated alkanesulfonyl or arysulfonyl, and their salts and esters. Such compounds inhibit the synthesis of cholesterol, and can be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.

    专利号:US-4996314-A
    优先权日:1986-03-11
    标题 :6-(disubstituted amino)carbapenem compounds
    发明人:YOSHIOKA TAKEO; CHIDA NORITAKA; WATANABE AZUMA; FUKAGAWA YASUO; ISHIKURA TOMOYUKI
    权利人:SANRAKU INC
    摘要:A compound represented by the formula ##STR1## wherein R 1 represents a lower alkyl group or a lower haloalkyl group; R 2 represents a lower alkyl group, a lower haloalkyl group, an aralkyl group, or a group of the formula --COOR 4 or --SO 2 R 5 in which R 4 represents an aralkyl group or a substituted or unsubstituted alkyl group and R 5 represents an alkyl group or a substituted or unsubstituted aryl group; and R 3 represents a hydrogen atom or a carboxyl protecting group which can be easily split off. This compound is useful in the production of a 6-(disubstituted amino)carbapenem-series antibiotic. n The compounds of the formula ##STR2## wherein R 1 and R 2 are as defined above are important intermediates for the synthesis of the compounds of formula (I) and/or the aforesaid di-(substituted amino) carbapenem-series antibiotics.

    专利号:US-3989685-A
    优先权日:1972-06-29
    标题 :Process for making a 2'-halopenicillin
    发明人:TANIDA HIROSHI; TSUJI TERUJI
    权利人:SHINOGI CO
    摘要:A 2'-halopenicillin compound is prepared from a penicillin-1-oxide compound by the action of an acid halide in the presence of a base. The product on heating rearranges to a 3-halo-3-methylcepham compound which itself gives a 3-methyl-3-cephem compound on further heating. A 2'-halopenicillin compound gives a 3-methyl-3-cephem compound on heating. The 2'-halopenicillin compounds, 3-halo-3-methylcepham compound and 3-methyl-3-cephem compounds are antibacterials which are also useful as intermediates for the synthesis of other penicillins and cephalosporins.

    专利号:US-5491167-A
    优先权日:1993-01-29
    标题 :Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses
    发明人:ISHIHARA SADAO; KOGEN HIROSHI; KOGA TEIICHIRO; KITAZAWA EIICHI; SERIZAWA NOBUFUSA
    权利人:SANKYO CO
    摘要:Compounds of formula (I): ##STR1## and their salts and esters have the ability to inhibit the synthesis of cholesterol, and can thus be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.

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    合成参考文献


    摘要:DiRocco, D. A.; Schultz, D. M., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 613.
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