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上下游产品

CAS号3972-65-4 对叔丁基溴苯 | CAS号6310-19-6 4-(叔丁基)-2-硝基苯胺 | CAS号5369-19-7 3-叔丁苯胺 | CAS号58164-14-0 2-溴-5-(叔丁基)苯胺

📜4-(叔丁基)-2-硝基苯胺置于溶剂黄146体系中,化学反应 8.0H,以2 G的收率获得产物1-溴-4-叔丁基-2-硝基苯
参考文献: Deoxynojirimycin Derivatives As Glucosidase Inhibitors[fr] Dérivés De Désoxynojirimycine En Tant Qu'Inhibiteurs De Glucosidase
标题: Deoxynojirimycin Derivatives As Glucosidase Inhibitors[fr] Dérivés De Désoxynojirimycine En Tant Qu'Inhibiteurs De Glucosidase
摘要:本申请提供了新颖的亚胺糖以及它们作为葡萄糖苷酶抑制剂的用途.本发明人发现某些脱氧诺吉霉素衍生物可能有效地抑制葡萄糖苷酶.特别是,这些脱氧诺吉霉素衍生物可能对治疗需要抑制葡萄糖苷酶的疾病或病况有用.

专利信息

专利号:US-6852711-B2
优先权日:1998-09-11
标题:HIV protease inhibitors
发明人：BOYER JR FREDERICK EARL; DOMAGALA JOHN MICHAEL; ELLSWORTH EDMUND LEE; GAJDA CHRISTOPHER ANDREW; HAGEN SUSAN ELIZABETH; LOVDAHL MICHAEL JAMES; LUNNEY ELIZABETH ANN; MARKOSKI LARRY JAMES; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:AGOURON PHARMA
摘要:The present invention relates to novel dihydropyrones with tethered heterocycles having improved pharmacologic properties which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of the dihydropyrones and intermediates useful in the preparation of the final compounds.