CAS: 64896-70-4; (3R,3Ar,6S,6Ar)-Hexahydrofuro[3,2-B]Furan-3,6-Diyl Dioctanoate

该化合物是六氟呋喃刀片的手性死亡衍生物,其特征是立体化学定义(3R,3aR,6S,6aR)配置.该复合物具有高度纯度和结构精度,适合用于不对称合成和制药中间体.辛醇酸酯组增强了脂性,提高了有机基质的溶性.其硬性双环状框架有助于在各种反应条件下的稳定.该产品在立体选择性变异中特别有用,其定义的性能确保了连贯一致的对应结果.在精细的化学合成中,它提供需要选择性和立体化学完整性的受控反应的可靠性能.

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物理性质

合成工艺路线路线简述

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    专利信息


    专利号:US-6693209-B2
    优先权日:2000-05-04
    标 题 :Synthesis of anhydroglycitol esters of improved colour
    发明人:VAN ES DANIEL STEPHAN; FRISSEN AUGUSTINUS EMMANUEL; LUITJES HENDRIKUS
    权利人:ATO BV
    摘要:Diesters of dianhydroglycitols can be prepared by esterification of dianhydroglycitols, anhydroglycitols and/or glycitols with alkylcarboxylic or arylcarboxylic acids in the presence of an acid catalyst, the acid catalyst being a macroporous acid ion exchange resin. If glycitols or monoanhydroglycitols are used as the starting material, the reaction temperature is initially of the order of 120° C. and after the dehydration is approximately 140° C.

    专利号:US-2003114635-A1
    优先权日:2000-05-04
    标题:Synthesis of anhydroglycitol esters of improved colour

    专利号:EP-1278752-B1
    优先权日:2000-05-04
    标题 :Improved synthesis of anhydroglycitol esters of improved colour

    专利号:EP-1278752-A1
    优先权日:2000-05-04
    标题:Improved synthesis of anhydroglycitol esters of improved colour

    专利号:WO-0183488-A1
    优先权日:2000-05-04
    标 题 :Improved synthesis of anhydroglycitol esters of improved colour

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