专利号:US-2024391773-A1 优先权日:2023-05-23 标 题 :Direct synthesis of improved superhydrophobic carbon nitride co-products, and improved superhydroppbic carbon nitride co-products thereof 发明人:LY THUC HUE; THI QUOC HUY; Man Ping 权利人:UNIV CITY HONG KONG 摘要:The present invention is concerned with a method of direct synthesis of co-products of at a first co-product and a second co-product. The first co-product is superhydrophilic carbon nitride thin film and the second co-product is superhydrophilic carbon nitride powder. The method has a step of using a guanidine carbonate salt as a precursor material. The present invention is also concerned with carbon nitride co-products. The carbon nitride co-products has a first co-product of superhydrophilic carbon nitride thin film and a second co-product of superhydrophilic carbon nitride powder. The superhydrophilic carbon nitride thin film has chemical formula of CN x , wherein x is 0.86-1.04, and the superhydrophilic carbon nitride powder has a chemical formula of g-C 3 N 4 .
专利号:US-9738647-B2 优先权日:2009-12-24 标题:Methods for the synthesis of polycyclic guanidine compounds 发明人:GRIDNEV ALEXEI 权利人:NOVOMER INC; SAUDI ARAMCO TECH CO 摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.
专利号:US-11584724-B2 优先权日:2018-04-23 标 题:Process for synthesis of a phenoxy diaminopyrimidine compound 发明人:MALONEY KEVIN M; BASU KALLOL; DI MASO MICHAEL JAMES; HUMPHREY GUY R; LEE ALFRED Y; PENG FENG; REN HONG; ZHANG SIWEI 权利人:MERCK SHARP & DOHME; WERTHENSTEIN BIOPHARMA GMBH; MERCK SHARP & DOHME LLC 摘要:Disclosed herein is a novel process for preparing Compound A free base, 5-((2,4-diaminopyrimidin-5-yl)oxy)-4-iso-propyl-2-methoxybenzenesulfonamide, and a citrate salt of Compound A with simplified chemistry and a high overall yield: Compound A. In one embodiment, the overall yield from the starting material 2-isopropylphenol to Compound A citrate salt is greater than 50%. In another embodiment, the overall yield is greater than 60%. Also disclosed herein are novel salts and solvates of Compound A.
专利号:US-5106750-A 优先权日:1988-08-30 标 题:Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents 发明人:WONG CHI-HUEY; WANG YI-FONG; HENNEN WILLIAM J; BABIAK KEVIN A; DYGOS JOHN H; NG JOHN S 权利人:SEARLE & CO 摘要:A process for irreversible regio- and stereoselective enzyme catalyzed acylation of alcohols using enol esters as acylating reagents is disclosed. The present invention permits the selective modification of hydroxyl group(s) of chiral and meso alcohols, including sugars, organometallics, and glycosides. The enol freed upon transesterification rapidly tautomerizes to the corresponding volatile aldehyde or ketone thereby preventing the reverse reaction from occurring.
专利号:US-9643934-B2 优先权日:2006-10-04 标 题:Process for synthesis of phenoxy diaminopyrimidine derivatives 发明人:DVORAK CHARLES ALOIS; GREEN KEENA LYNN; LEE GARY R 权利人:ROCHE PALO ALTO LLC 摘要:A method for preparing a compound of formula k n n n n n n n n n n n n or a salt or solvate thereof,n wherein R 1 is as defined herein, n n the method comprising treating a compound of formula j n n n n n n n n n n n n n n n n or a salt or solvate thereof, n with ammonia, to form the compound of formula k.
专利号:US-4151196-A 优先权日:1975-06-26 标题 :Cyano-enol ethers 发明人:ROSEN PERRY 权利人:HOFFMANN LA ROCHE 摘要:The present invention relates to a new synthesis for the preparation of 5-(substituted benzyl)-2,4-diamino-pyrimidines, including new pyrimidine derivatives. More particularly, a new synthesis of ormetoprin, diaveridine and related compounds, including novel derivatives, is disclosed. The synthesis involves the condensation of a substituted benzene and an acrylonitrile derivative to directly give enol ether intermediates, which upon subsequent reaction by known techniques with guanidine, provides the desired 5-(substituted benzyl)-2,4-diamino-pyrimidines, including novel compounds. The pyrimidine end products are useful as potentiators of sulfonamides and as antibacterial agents.