CAS: 59291-64-4; 2,2',3,4,4',6'-Hexachlorobiphenyl
该化合物是一种属于多氯联苯(PCB)家族的氯化联苯化合物,其特征是,在联苯结构上有六个氯原子对称替代,有助于其化学稳定性和亲脂性,该化合物主要因其环境持久性和毒理特性而进行了研究,成为多氯联苯检测和量化的分析化学参考标准,其结构定义明确,纯度高,适于研究应用,包括环境监测,毒理学研究和监管合规测试.由于其持久性和生物累积性潜力,处理需要遵守严格的安全议定书.
- 英文名称2,2',3,4,4',6'-Hexachlorobiphenyl
- 中文名称2,2',3,4,4',6'-六氯联苯
- IUPAC名称1,2,3-trichloro-4-(2,4,6-trichlorophenyl)benzene
- 其它别名2,2',3,4,4',6'-Hexachlorobiphenyl; 2,3,4,2',4',6'-Hexachlorobiphenyl
- CAS编号59291-64-4
- FDA UNII编号:I0T35AMK10
- 分子式:C12H4Cl6分子量:360.882
- 产品CID: 1569544
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: XBBRGUHRZBZMPP-UHFFFAOYSA-N
- 1S/C12H4Cl6/c13-5-3-8(15)10(9(16)4-5)6-1-2-7(14)12(18)11(6)17/h1-4H
- 计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
2,4,6-trichloroaniline 1,2,3-trichlorobenzene合成工艺路线路线简述
📜2,4,6-三氯苯胺,三氯苯置于亚硝酸异戊酯体系中,化学反应生成 2,2',3,4,4',6'-六氯联苯
参考文献:Sandstroem,G.; Wachtmeister,C.A.,Acta Chemica Scandinavica (1947),1972,Vol. 26,P. 3816-3818
标题:Sandstroem,G.; Wachtmeister,C.A.,Acta Chemica Scandinavica (1947),1972,Vol. 26,P. 3816-3818
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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