CAS: 42885-14-3; 5-Methylpyridine-3-Carbonitrile

相似化合物

3222-49-9 100910-66-5 1195-58-0

上下游产品

sodium cyanide 5-methylpyridinylcarboxamide CYANAMID propyl 5-methyl-3-pyridinecarboximidate 5-methylnicotinic acid methyl ester 3-methyl-5-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine 4-[2-(5-methylpyridin-3-yl)-4-(trifluoromethyl)-1H-imidazol-1-yl]benzenesulfonamide (+/-)-5-Methylnicotine

📜5-甲基烟酰氨置于三氟乙酸酐体系中,用 二氯甲烷,水,三乙胺 作为反应溶剂,化学反应生成 2-氰基-5-甲基吡啶
参考文献:1,2-Aryl And Heteroaryl Substituted Imidazolyl Compounds For The
标题:1,2-Aryl And Heteroaryl Substituted Imidazolyl Compounds For The
摘要:描述了一类咪唑基化合物,用于治疗炎症和与炎症相关的疾病.特别感兴趣的化合物由以下式i定义:##str1##其中r.Sup.1-R.Sup.6如规范中所述;或其药用盐.

专利信息

专利号:US-8981092-B2
优先权日:2008-09-19
标题 :Substituted 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-ones as modulators of protein kinase activity
发明人：MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO
权利人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO; NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, n nor pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

专利号:US-3160633-A
优先权日:1962-12-06
标 题:Synthesis of pyridine aldehydes
发明人：CISLAK FRANCIS E
权利人:REILLY TAR & CHEM CORP

专利号:US-3155677-A
优先权日:1962-12-10
标题:Synthesis of pyridyl alkyl ketones
发明人：FELDHAKE RALPH H
权利人:REILLY TAR & CHEM CORP

专利号:US-9611264-B1
优先权日:2015-09-24
标 题:N-[2-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl] amides
发明人：BRODNEY MICHAEL AARON; BUTLER CHRISTOPHER RYAN; ZHANG LEI; O'NEILL BRIAN THOMAS; VERHOEST PATRICK ROBERT; SALOMON FERRER ROMELIA DEL CARMEN
权利人:PFIZER
摘要:The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, n n n n n n n n n n n n wherein the variables R 1 , R 2 and R 3 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.