CAS: 2305750-23-4; Im-205
- 英文名称Im-205
- 中文名称(S)-2-(2',5'-二氟-[1,1'-']-4-基)-N-甲基-N-(4-甲基-5-(S-S)噻唑-2-基)乙酰胺
- IUPAC名称(S)-2-(2',5'-difluoro-[1,1'-biphenyl]-4-yl)-N-methyl-N-(4-methyl-5-(S-methylsulfonimidoyl)thiazol-2-yl)acetamide
- 其它别名[1,1′-Biphenyl]-4-Acetamide, 2′,5′-Difluoro-N-Methyl-N-[4-Methyl-5-[[s(S)]-S-Methylsulfonimidoyl]-2-Thiazolyl]-
- CAS编号2305750-23-4
- FDA UNII编号:6ZQ8Q3CB8R
- 分子式:C20H19F2N3O2S2分子量:435.52
- 产品CID: 2168418
- 同类组份化合物CAS2305750-23-4 (free base)2954725-84-7 (HCl)2954725-85-8 (HBr)
- 产品分类Inhibitors/Agonists → Anti-infection → HSV | Inhibitors/Agonists → Anti-infection → Antiviral
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2912110000-甲醛
2912120000-乙醛
2924199090-其他无环酰胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Bay C, Bergamino M, Sauter M, Czock D, Gege C, Blank A, Kleymann G, Burhenne J. A UPLC-MS/MS assay for the quantification of the novel viral helicase-primase drug candidate adibelivir (IM-250) in human specimen. J Chromatogr B Analyt Technol Biomed Life Sci. 2026 May 1;1275:124995. doi: 10.1016/j.jchromb.2026.124995. Epub 2026 Feb 26.
243:106271. doi: 10.1016/j.antiviral.2025.106271. Epub 2025 Sep 3. 35(10):1039-1050. doi: 10.1080/13543776.2025.2548925. Epub 2025 Aug 26. 34(10):863-872. doi: 10.1080/13543776.2024.2403618. Epub 2024 Sep 17.
106:129761. doi: 10.1016/j.bmcl.2024.129761. Epub 2024 Apr 19.
合成参考文献
参考文献:10.1016/j.bmcl.2024.129761
摘要:Gege C, Kleymann G. Replacement of sulfonamide by sulfoximine within a helicase-primase inhibitor with restricted flexibility. Bioorganic & Medicinal Chemistry Letters. 2024 Jul;106():129761. doi: 10.1016/j.bmcl.2024.129761.
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