CAS: 2081-44-9; Tetrahydro-2H-Pyran-4-Ol

相似化合物

97986-34-0 29943-42-8 7525-64-6

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CAS号29943-42-8 四氢吡喃酮 | CAS号110-88-3 三聚甲醛 | CAS号627-27-0 3-丁烯-1-醇 | CAS号542-05-2 1,3-丙酮二羧酸 | CAS号78870-52-7 (+/-)-3,4-epoxy... | CAS号108-97-4 4H-吡喃-4-酮 | CAS号50-00-0 甲醛 | CAS号187737-37-7 propene | CAS号64-17-5 乙醇 | CAS号99-32-1 白屈菜酸 | CAS号1040377-02-3 4-溴-1-(四氢-2H-吡喃... | CAS号3393-45-1 5,6-二氢-2H-吡喃-2-酮 | CAS号494772-07-5 5-溴-2-(四氢吡喃-4-氧基)吡啶 | CAS号50675-18-8 四氢吡喃-4-甲醛 | CAS号38041-19-9 4-氨基四氢吡喃 | CAS号215453-84-2 4-(4-溴苯氧基)四氢-2H-吡喃 | CAS号203246-70-2 S-(oxan-4-yl) e... | CAS号20638-52-2 4-苯基四氢吡喃 | CAS号85064-61-5 四氢吡喃-4-乙酸 | CAS号1040377-03-4 1-(四氢吡喃-4-基)-1H...

1,3-丙酮二羧酸置于indium(III) Bromide,1,1,3,3-四甲基二硅氧烷体系中,用 甲苯 用作溶剂,化学反应 1.0H,以17%的收率获得四氢吡喃-4-醇
参考文献:通过 Inbr3/tmds 环化二羧酸合成 3-取代四氢呋喃和 4-取代四氢吡喃衍生物
标题:通过 Inbr3/tmds 环化二羧酸合成 3-取代四氢呋喃和 4-取代四氢吡喃衍生物
摘要:据报道,使用 Inbr3/tmds 系统对二酸化合物进行有效还原,然后环化.该系统允许形成在 3 位或 4 位取代的五元和六元环醚.
Doi:10.1002/ejoc.201200727

专利信息

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人：BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

专利号:US-10040775-B2
优先权日:2014-10-18
标 题:Synthesis of chirally enriched 2,4-disubstituted tetrahydropyran-4-ol and its derivatives
发明人：BHAT SUJATA V; GAIKWAD RAVINDRA D; VAZE KEDAR R
权利人:S H KELKAR AND COMPANY LTD
摘要:The present invention discloses a process for synthesis of chiral 2,4-disubstituted-tetrahydropyran-4-ol and its derivatives having a general formula (I) comprising of asymmetric reaction of an aliphatic aldehyde and a homoallylic alcohol in the presence of a chiral organocatalyst, and a fragrance and cosmetic composition containing chirally enriched molecules of the said general formula (I) prepared by the aforesaid process.

专利号:US-5567830-A
优先权日:1994-02-14
标题 :Process for synthesis of acetylenic carbinols
发明人：UPASANI RAVINDRA B
权利人:COCENSYS INC
摘要:A method for the preparation of an acetylenic alcohol by reaction of 1,2-dibromoethylene with an alkyl, aryl an heteroaryl lithium in an inert solvent, followed by reaction with a carbonyl-containing compound to give an acetylenic alcohol is disclosed.

专利号:US-5637757-A
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds
发明人：HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
权利人:GREAT LAKES CHEMICAL CORP
摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人：HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-2007021436-A1
优先权日:2005-06-10
标 题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis