CAS: 183673-66-7; N-Boc-4-(Fmoc-Amino)Piperidine-4-Carboxylic Acid

相似化合物

183673-71-4 288154-16-5 189321-65-1

上下游产品

CAS号82911-69-1 9-芴甲基-N-琥珀酰亚胺碳酸酯 | CAS号183673-71-4 1-B°C-4-氨基哌啶-4-甲酸 | CAS号40064-34-4 4,4-哌啶二醇盐酸盐 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号79099-07-3 1-B°C-4-哌啶酮 | CAS号13625-39-3 1,3,8-三氮杂螺[4.5]... | CAS号183673-70-3 8-B°C-2,4,8-三氮杂... | CAS号183673-68-9 2,4-二氧代-1,3,8-三... | CAS号102774-86-7 (9H-芴-9-基)甲基 2,... | CAS号368866-09-5 4-(Fm°C-氨基)-4-哌...

📜2,4-二氧代-1,3,8-三氮杂螺[4,5]癸烷-8-甲酸叔丁酯置于4-二甲氨基吡啶,Sodium Hydroxide体系中,用 四氢呋喃,乙二醇二甲醚,水 用作溶剂,化学反应 44.0H,反应生成1-(N-Boc)-4-(N-Fmoc-氨基)-4-哌啶甲酸
参考文献:4-Aminopiperidine-4-Carboxylic Acid: A Cyclic α,α-Disubstituted Amino Acid For Preparation Of Water-Soluble Highly Helical Peptides
标题:4-Aminopiperidine-4-Carboxylic Acid: A Cyclic α,α-Disubstituted Amino Acid For Preparation Of Water-Soluble Highly Helical Peptides
摘要:
Doi:10.1021/jo961594K

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-9926293-B2
优先权日:2014-05-30
标题 :Multivalent RAS binding compounds
发明人：STOCKWELL BRENT R; WELSCH MATTHEW
权利人:UNIV COLUMBIA
摘要:The present invention provides, inter alia, compounds having the structure: n nwherein R 7 , R 8 and n are as disclosed herein, that selectively bind a RAS protein at two or more sites and methods for their synthesis. Compositions and kits containing the compounds, as well as methods of using the compounds and compositions for ameliorating or treating the effects of a disease associated with altered RAS signaling, such as a cancer, in a subject and methods for effecting cancer cell death are also provided herein. Methods of identifying a multivalent compound which binds selectively to a target protein also are provided herein.

专利号:CN-118878622-A
优先权日:2024-09-27
标 题:Green chemical synthesis method of illegal stand