CAS: 1376615-97-2; (Z)-2-(11-(3-(Dimethylamino)Propylidene)-6,11-Dihydrodibenzo[b,E]Oxepin-2-yl)Acetaldehyde

上下游产品

奥洛他定 Olopatadine 113806-05-6
(Z)-2-(11-(3-(Dimethylamino)Propylidene)-6,11-Dihydrodibenzo[b,E]Oxepin-2-yl)-N-Methoxy-N-Methylacetamide 1376615-92-7

📜奥洛他定置于二异丁基氢化铝,1-羟基苯并三唑,盐酸-N-乙基-N'-(3-二甲氨基丙基)碳二亚胺,三乙胺体系中,用 正己烷,二氯甲烷 用作溶剂,化学反应 17.0H,反应生成奥洛他定甲醛
参考文献:Drug Derivatives
标题:Drug Derivatives
摘要:本发明涉及已知活性药物化合物的衍生物.这些衍生物通过是活性化合物的氧化还原衍生物与母体活性化合物相区别.这意示活性化合物中的一个或多个官能团已转化为另一组,在一项或多项反应中,这可以被认为代表氧化态的变化.我们通常将这些化合物称为氧化还原衍生物.发明中的衍生物可能与原始母体活性药物化合物仅通过单一步骤转换有关,或者可能通过包括一个或多个氧化态变化的几个合成步骤与之相关.在某些情况下,经过两个或更多转换后获得的官能团可能与母体活性化合物处于相同的氧化态(我们将这些化合物包括在我们的氧化还原衍生物定义中).在其他情况下,发明的衍生物的氧化态可以被认为是与母体化合物不同的.在许多情况下,发明中的化合物本身就具有固有的治疗活性.在某些情况下,相对于母体化合物的相同靶点或靶点,这种活性与母体化合物针对该靶点或靶点的活性一样好或更好.

专利信息

专利号:WO-9403902-A1
优先权日:1992-08-03
标 题:Method and device for producing energy and obtaining tritium, helium and free neutrons
发明人：KIRKINSKY VITALY ALEXEEVICH
权利人:KIRKINSKY VITALY ALEXEEVICH
摘要:A method for producing energy which is based on the phenomenon of cold nuclear synthesis at sorption-desorption of deuterium in metals, characterized by the use, as the metals, of elements or alloys forming two crystalline phases with different content of deuterium consisting in equilibrium within a certain temperature and pressure range and mutually isostructural, for example palladium, niobium, vanadium, rare earth elements, intermetallic compounds TiFe and TiCr2. The metal is prepared in the form of powder (with the size of particles less than 0.1 mm), thin foil, a film on a substrate, a wire or compact mass with pores and microcracks with the largest possible total surface. The techniques for preparation of the metal and for carrying out the method are elaborated. Sorption is carried out at a deuterium pressure exceeding that of three-phase equilibrium of the isostructural phases with the gas at a given temperature which is below the critical one, whereas desorption is carried out under the conditions of two-phase equilibrium of the crystalline phase with the gas at a pressure which is below the critical pressure of the equilibrium of the isostructural phases. The cycle is continuously repeated. The method allows to accelerate by several orders of magnitude the process of cold nuclear synthesis and to make more comfortable and secure the use of the produced energy.

专利号:US-2513994-A
优先权日:1946-12-31
标 题:Production of synthesis gas
发明人：DAVIDSON DONALD D
权利人:SHELL DEV