CAS: 1263279-47-5; Tert-Butyl 5'-Oxo-8-Azaspiro[bicyclo[3.2.1]Octane-3,3'-Pyrrolidine]-8-Carboxylate

相似化合物

1246646-23-0 169206-67-1 1873305-94-2

📜Tert-Butyl 3-(2-Ethoxy-2-Oxoethyl)-3-(Nitromethyl)-8-Azabicyclo[3.2.1]octane-8-Carboxylate置于platinum(Iv) Oxide,氢气体系中,用 2,2,2-三氟乙醇 用作溶剂,以54 %的收率获得5-氧代-螺[8-氮杂双环[3.2.1]辛烷-3,3-吡咯烷]-8-羧酸 1,1-二甲基乙酯
参考文献: Small Molecule Modulators Of Glucocerebrosidase Activity And Uses Thereof[fr] Modulateurs à Petites Molécules De L'Activité Glucocérébrosidase Et Leurs Utilisations
标题: Small Molecule Modulators Of Glucocerebrosidase Activity And Uses Thereof[fr] Modulateurs à Petites Molécules De L'Activité Glucocérébrosidase Et Leurs Utilisations
摘要:Provided Herein Are Compounds That Modulate Glucocerebrosidase (Gcase),An Enzyme Whose Activity Is Associated With Neurological Diseases And Disorders (E.G.,Gaucher'S Disease,Parkinson'S Disease). Also Provided Are Pharmaceutical Compositions And Kits Comprising The Compounds,And Methods Of Treating Gcase-Related Diseases And Disorders (E.G.,Gaucher'S Disease,Parkinson'S Disease) With The Compounds In A Subject,By Administering The Compounds And/or Compositions Described Herein.