CAS: 91367-05-4; Methyl 4-Chloro-3-Methylbenzoate

该化合物是有机化合物,其特征为酯性功能组,产自苯甲酸,其成分为甲基组,芳香环上替代氯原子,该化合物一般视纯度和温度而定,无色可粉黄黄色液体或固体,以有机溶剂中的中溶性及水溶性有限而闻名,许多芳香酯都常见.氯原子的存在可产生独特的再活动,影响化合物的物理特性,如沸点和熔点.此外,该混合物可能展示生物活动,使其在包括制药和农用化学品在内的各个领域引起兴趣.在处理和接触准则方面,应参考安全数据,因为卤化化合物可能对环境和健康造成危害.总体而言,苯化酸,4-氯-3-甲基甲基甲基,甲基酯是有机化学中一种显著的化合物,可能用于合成和研究.

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上下游产品

CAS号7697-29-2 4-氯-3-甲基苯甲酸 | CAS号74-88-4 碘甲烷 | CAS号18595-14-7 4-氨基-3-甲基苯甲酸甲酯 | CAS号220464-68-6 3-(溴甲基)-4-氯苯甲酸甲酯

合成工艺路线路线简述

  • 18595-14-7 = 91367-05-4
    反应条件:1.1 Reagents: Sodium Nitrite,Hydrochloric Acid,Cuprous Chloride Solvents: Water; 0 - 5 °C
    标题:Design,Synthesis And Identification Of Novel Colchicine-Derived Immunosuppressant
    作者:Chang,Dong-Jo; Yoon,Eun-Young; Lee,Geon-Bong; Kim,Soon-Ok; Kim,Wan-Joo; Et Al
    参考文献:Bioorganic & Medicinal Chemistry Letters 日期:2009 卷标:19(15) 页码:4416-4420]

    7697-29-2 = 91367-05-4
    反应条件:1.1 Reagents: Sulfuric Acid Solvents: Methanol; 8 H,Reflux
    标题:Design,Synthesis And Evaluation Of Novel 2-(1H-Imidazol-2-Yl) Pyridine Sorafenib Derivatives As Potential Braf Inhibitors And Anti-Tumor Agents
    作者:Jiao,Yu; Xin,Bo-Tao; Zhang,Yanmin; Wu,Jianbing; Lu,Xiaolin; Et Al
    参考文献:European Journal Of Medicinal Chemistry 日期:2015 卷标:90 页码:170-183
📜4-氨基-3-甲基苯甲酸甲酯置于盐酸,Copper(L) Chloride,Sodium Nitrite体系中,用 水 作为反应溶剂,化学反应生成 4-氯-3-甲基苯甲酸甲酯
参考文献:Design,Synthesis And Identification Of Novel Colchicine-Derived Immunosuppressant
标题:Design,Synthesis And Identification Of Novel Colchicine-Derived Immunosuppressant
摘要:Synthesis And Biological Evaluation Of Various Colchicine Analogues Through The Mixed-Lymphocyte Reaction (Mlr),Lymphoproliferation,And Inhibitory Effects On The Inflammatory Genes Are Described. In Addition,A New Series Of Immunosuppressive Agents Developed On The Structural Basis Of Colchicine,As Well As Their Structure-Activity Relationships Is Reported. The Most Potent Analogue 20A Exhibited An Excellent Immunosuppressive Activity On In Vivo Skin-Allograft Model,Which Is Comparable To That Of Cyclosporin A. (C) 2009 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2009.05.054

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