5-(溴甲基)呋喃-2-甲醛置于水,Silver(L) Oxide体系中,化学反应生成 5-羟甲基-2-呋喃甲酸 参考文献:Fenton; Gostling,Journal Of The Chemical Society,1899,Vol. 75,P. 424 标题:Fenton; Gostling,Journal Of The Chemical Society,1899,Vol. 75,P. 424
专利号:US-2024368099-A1 优先权日:2022-01-18 标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes 发明人:SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS 权利人:HENKEL AG & CO KGAA 摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.
专利号:US-9359318-B2 优先权日:2010-08-06 标 题:Process for the synthesis of 2,5-furandicarboxylic acid 发明人:BORSOTTI GIAMPIETRO; DIGIOIA FRANCESCA 权利人:BORSOTTI GIAMPIETRO; DIGIOIA FRANCESCA; NOVAMONT SPA 摘要:Process for the synthesis of 2,5-furandicarboxylic acid through the oxidation of -hydroxymethylfurfural in a flow of oxygenor a compound containing oxygen, catalyzed by a supported catalyst containing a metal of the platinum group, carried out in aqueous solution in which the pH is maintained higher than 7 and lower than 12 through the addition of a weak base.
专利号:US-12384755-B2 优先权日:2019-12-19 标 题:Process for the synthesis of Furandicarboxylic acid 发明人:RODE CHANDRASHEKHAR VASANT; DHARNE MAHESH SHANTAPPA; PARATE ROOPA DHANRAJ 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides a process for the synthesis of Furandicarboxylic acid (FDCA) comprising heating a mixture of fructose, aqueous NaCl or KCl, solvent, methyl isobutyl ketone (MIBK) and a catalyst at a temperature in the range of 150 to 200° C. in a sealed vessel for a time period in the range of 2 to 5 hours to yield crude 5-(hydroxymethyl)furfural (5-HMF). The crude 5-HMF further reacts with a biocatalyst at a temperature in a range of 20 to 50° C. for a period at a range of 24 to 96 hours to yield FDCA, wherein the conversion of 5-HMF to FDCA is in the range of 90 to 100%.
专利号:US-11034986-B1 优先权日:2017-07-25 标 题:Comamonas testosteroni strain and use thereof for the synthesis of 5-hydroxymethyl-2-furancarboxylic acid 发明人:LI NING; ZHANG XUEYING; ZONG MINHUA 权利人:UNIV SOUTH CHINA TECH 摘要:The present invention provides a Comamonas testosteroni strain and use thereof for the synthesis of 5-hydroxymethyl-2-furancarboxylic acid, wherein the strain is Comamonas testosteroni SC1588, maintained in China Center for Type Culture Collection, CCTCC for short, on Oct. 13, 2016, with an accession number of CCTCC NO: M 2016562.
专利号:WO-2019170204-A1 优先权日:2018-03-05 标 题 :Synthesis of precursors of 2,5-furandicarboxylic acid 发明人:PEDERSEN MARTIN; PEDERSEN CHRISTIAN 权利人:UNIV COPENHAGEN 摘要:The present invention relates to a method for the manufacture of stable FDCA precursors from saccharide derived starting materials. More specific the invention relates to the synthesis of FDCA precursors such as alkyl 5-(hydroxymethyl)furan-2-carboxylates or 5-(hydroxymethyl)furan-2-carboxylic acid in an expedient, practical and environmental benign manner from e.g. D-glucono-δ-lactone. These bio-based monomer building blocks hold great potential in the manufacture of polymer materials.
专利号:US-11607677-B2 优先权日:2017-10-30 标 题:Homogeneous and reusable superacid polymer catalyst useful for the synthesis of 5-hydroxymethylfurfural from glucose 发明人:ALBA RUBIO ANA C; COLEMAN MARIA R; KALIDINDI SUBHASH; JOSHI ANUP S; OMODOLOR IBEH S 权利人:UNIV TOLEDO; TJIE UNIV OF TOLEDO 摘要:A superacid polymeric catalyst having both Lewis acidity and Brønsted acidity is described, along with methods of making and methods of using the same.
[参考文献]: D.Jöbstl, Et Al. Analysis Of 5-Hydroxymethyl-2-Furoic Acid (Hmfa) The Main Metabolite Of Alimentary 5-Hydroxymethyl-2-Furfural (Hmf) With Hplc And Gc In Urine. Food Chemistry. 2010 Dec 1; 123 (3): 814-818.
合成参考文献
参考文献:10.1107/s1600536811019489 摘要:Liu JL, Xu QY. 5-(Hy-droxy-meth-yl)furan-2-carb-oxy-lic acid. Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 01;67(Pt 6):o1548.