CAS: 54132-75-1; 3,5-Dimethylphenylisocyanate

相似化合物

621-29-4 51163-27-0 622-58-2

上下游产品

CAS号75-44-5 光气 | CAS号108-69-0 3,5-二甲基苯胺 | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号32315-10-9 三光气 | CAS号864269-47-6 [((CH(C(Me)N-2,... | CAS号70334-59-7 1-azido-3,5-dim... | CAS号590-28-3 氰酸钾 | CAS号88451-14-3 1-benzyl-1-buty...

Allyl 3,5-(Dimethyl)Phenylcarbamate置于2-氯吡啶,三氟甲磺酸酐体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.08H,反应生成 3,5-二甲基苯基异氰酸酯
参考文献:N-Alloc-,N-Boc-和 N-Cbz 保护胺在温和条件下的实用一锅酰胺化
标题:N-Alloc-,N-Boc-和 N-Cbz 保护胺在温和条件下的实用一锅酰胺化
摘要:已经描述了由n-Alloc-,N-Boc-和n-Cbz-保护的胺轻松一锅合成酰胺.该反应涉及使用在 2-氯吡啶和三氟甲磺酰酐存在下原位反应生成的异氰酸酯中间体与格氏试剂反应反应生成相应的酰胺.使用该反应方案,多种n-Alloc-,N-Boc-和n-Cbz-保护的脂肪胺和芳基胺以高产率有效地转化为酰胺.该方法对酰胺的合成非常有效,并为简便的酰胺化提供了一种有前途的方法.
DOI:10.1039/d1Ra02242C

专利信息

专利号:US-12338202-B2
优先权日:2021-09-10
标 题 :One pot synthesis of urea (meth)acrylates
发明人：BESTGEN SEBASTIAN; BEYER SILVIA
权利人:EVONIK OPERATIONS GMBH
摘要:A one-pot synthesis of polymerizable and acyclic urea (meth)acrylates, preferably mono(meth)acrylates, can be performed via in-situ synthesis of urea alcohols or amines followed by direct reaction with a (meth)acrylate reactive diluent. The urea alcohol/amine is obtained from isocyanates and alcohols, amines, or hydroxyamines. Subsequently, the reaction with the (meth)acrylate reactive diluent takes place and the urea (meth)acrylate is directly obtained either in solution with the reactive diluent, or as a pure material after removal of the reactive diluent.

专利号:US-6528642-B1
优先权日:1997-08-29
标题:Mono-and di-derivatives of cyclodextrins, synthesis thereof and purification and use thereof in support
发明人：DUVAL RAPHAEL; LEVEQUE HUBERT
权利人:INST FRANCAIS DU PETROLE; CHIRALSEP SARL
摘要:Mono- and di-derivatives of cyclodextrins are completely defined, also a method for their synthesis and purification, functionalised cyclodextrins obtained from these derivatives, and the synthesis of supports comprising these cyclodextrin derivatives. Use of the supports for the preparation or separation of enantiomers, for asymmetric synthesis, for catalysis, for the preparation or separation of geometrical isomers or positional isomers, or for the preparation or separation of organic molecules with a hydrophobic nature is also described.

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-7825240-B2
优先权日:1998-09-11
标题:Cross-linked polymers based on bis-silane, bis-thioether, bis-sulphoxide, bis-sulphone and butane-di-yl derivatives of polysaccharides and oligosaccharides, and their shaping as support materials
发明人：DUVAL RAPHAEL
权利人:EKA CHEMICALS AB
摘要:There are described novel cross-linked polymers based on bis-silane, bis-thioether, bis-sulphoxide, bis-sulphone and butane-di-yl derivatives of polysaccharides and oligosaccharides, their shaping as support materials useful for the separation or preparation of enantiomers; a process for preparing the said cross-linked polymer compounds, a process for preparing balls of support materials containing the said cross-linked polymer compounds; a method of obtaining balls of support materials useful in chromatography or in organic synthesis; and the use of the said support materials containing the cross-linked polymer compounds in separation or in preparation of enantiomers, through employment in chromatography or organic synthesis processes in a heterogeneous medium; and the use of the said cross-linked polymer compounds in the form of membranes in processes using percolation through membranes for the separation or the preparation of enantiomers.

专利号:US-7067640-B1
优先权日:1997-03-14
标题:Cross-linked chiral compounds and methods of making thereof
发明人：DUVAL RAPHAEL; LEVEQUE HUBERT
权利人:EKA CHEMICALS AB
摘要:The invention relates to a method which comprises synthesizing bifunctional compounds then chiral compounds from the bifunctional compounds, also to synthesizing supports comprising these chiral compounds, and the use of these supports for preparing or separating enantiomers, or for asymmetric synthesis. The invention also relates to bifunctional compounds, their use as a source of functionalized polymers, and to the chiral compounds, also to the use of these chiral compounds in a chiral support in the form of a three-dimensional network or for separating or preparing enantiomers, principally for analytical or preparative chromatography, and in a support for the production of chiral molecules by asymmetric synthesis.

专利号:US-2023101100-A1
优先权日:2021-09-10
标题:One Pot Synthesis of Urea (Meth)Acrylates