CAS: 541-07-1; 3-Hydroxy-3-Methyl-Glutaraldehyd-Saeure (Mevaldinsaeure)

上下游产品

3-Hydroxy-5,5-Dimethoxy-3-Methylpentansaeure 32039-76-2

📜3-Hydroxy-5,5-Dimethoxy-3-Methylpentansaeure置于acidic Cationen-Exchanger,水体系中,化学反应生成 3-羟基-3-甲基戊二醛酸
参考文献:Eggerer; Lynen,Justus Liebigs Annalen Der Chemie,1957,Vol. 608,P. 71,77
标题:Eggerer; Lynen,Justus Liebigs Annalen Der Chemie,1957,Vol. 608,P. 71,77

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.