CAS: 492-98-8; 1H,1'H-2,2'-Biimidazole

该化合物是有机化合物,其独特结构由两枚由碳-碳联结连接的无脊椎环组成.该化合物是白的,白的晶状固体,在水和酒精等极地溶剂中溶解,但在非极地溶剂中不易溶解.该化合物具有有趣的化学特性,包括能够作为诱导性螺丝,在各协调综合体中与金属离子协调. 2,2欧元比米达索尔因其在生物系统中的作用而著称,特别是在稳定某些酶结构和功能方面.此外,它还在有机合成和材料科学中应用,用于聚合物的开发,并用作较复杂的分子的建筑块块.该化合物还被研究其在制药和各种化学反应中作为催化剂的潜在用途.其稳定性和再活性使它在学术研究和工业应用中成为有价值的化合物.

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37570-94-8 874116-35-5 98138-00-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

3,3,3-trichloro-2-hydroxy-propionic acid Glyoxal ammonium acetate glyoxal sulfate 1,1′-dibenzyl-2,2′-biimidazole 1,1'-dimethyl-2,2'-biimidazole N-benzyl-2,2'-bi-1H-imidazole 4-benzyl-2,2'-bi-1H-imidazole

合成工艺路线路线简述

    📜1,2-Dihydroxyethylenediamine Dihydrochloride置于sodium Acetate体系中,用 水 作为反应溶剂,化学反应 2.0H,以60.4%的收率获得产物联咪唑
    参考文献:Syntheses Of 2,2-Diimidazole
    标题:Syntheses Of 2,2-Diimidazole
    摘要:
    DOI:10.1007/bf00473456

    专利信息


    专利号:US-8084569-B2
    优先权日:2006-12-21
    标 题 :Process for the synthesis of diaminopyridines from glutarimidines
    发明人:MINTER AARON; STOKES BERLIN
    权利人:MINTER AARON; STOKES BERLIN; DU PONT
    摘要:A liquid-phase process is provided for the synthesis from glutarimidines of diaminopyridines and related compounds, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a dehydrogenative aromatization process.

    专利号:US-7999057-B2
    优先权日:2008-07-08
    标 题:Gas-phase process for the synthesis of diaminopyridines from glutaronitriles
    发明人:HUTCHENSON KEITH W; MINTER AARON; SUNSHINE GREGG
    权利人:DU PONT
    摘要:A gas-phase, continuous process is provided for the manufacture of 2,6-diaminopyridine and related compounds from glutaronitriles, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a dehydrogenative aromatization process.

    专利号:US-2011301314-A1
    优先权日:2008-12-18
    标题:Continuous liquid-phase process for the synthesis of diaminopyridines from glutaronitriles
    发明人:HUTCHENSON KEITH W; MINTER AARON
    权利人:HUTCHENSON KEITH W; MINTER AARON; DU PONT
    摘要:A liquid-phase, continuous process is provided for the manufacture of 2,6-diaminopyridine and related compounds from glutaronitriles, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a dehydrogenative aromatization process.

    专利号:US-8637695-B2
    优先权日:2011-12-30
    标 题:Synthesis of organohalosilane monomers from conventionally uncleavable Direct Process Residue
    发明人:LEWIS KENRICK MARTIN; NEELY JOHN DAVID
    权利人:LEWIS KENRICK MARTIN; NEELY JOHN DAVID; MOMENTIVE PERFORMANCE MAT INC
    摘要:Disclosed herein is a catalytic process for the synthesis of organohalosilane monomers from tetraorganodihalodisilanes and other compounds that are not cleaved during the conventional hydrochlorination of Direct Process Residue. The process is characterized by the use of a catalyst containing (1) one or more heterocyclic amines and/or one or more heterocyclic ammonium halides, and (2) one or more quaternary Group 15 onium compounds.

    专利号:US-7429658-B2
    优先权日:2003-09-11
    标题 :Synthesis of protected pyrrolobenzodiazepines
    发明人:HOWARD PHILIP; MASTERSON LUKE
    权利人:SPIROGEN LTD
    摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

    专利号:US-7557099-B2
    优先权日:2004-03-01
    标题 :Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
    发明人:HOWARD PHILIP WILSON; KANG GYOUNG-DONG
    权利人:SPIROGEN LTD
    摘要:Compounds and a method of synthesis of compounds of formula (Ia) or (Ib): and salts, solvates, and chemically protected forms thereof, wherein the dotted lines indicate the optional presence of a double bond between C1 and C2 or C2 and C3; R 2 and R 3 are independently selected from —H, â•?O, â•?CH 2 , —CN, —R, OR, halo, â•?CH—R, O—SO 2 —R, CO 2 R and COR; R 10 is a carbamate-based nitrogen protecting group; and R 11 is an oxygen protecting group.

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    合成参考文献


    参考文献:10.1107/s1600536810028175
    摘要:Zhang Y, Jin Q, Yang W, Zhang C. Tetraaqua(1,10-phenanthroline-κ2N,N′)cadmium(II) sulfate dihydrate. Acta Crystallogr E Struct Rep Online. 2010 Jul 21;66(8):m970. doi: 10.1107/s1600536810028175.
    参考文献:10.1107/s1600536810031922
    摘要:Dai Y, Jin Q, Cui L, Xu L, Zhang C. Bis(2,2′-bi-1H-imidazole-κ2N3,N3′)bis(dimethyl sulfoxide-κO)copper(II) bis(tetrafluoridoborate). Acta Crystallogr E Struct Rep Online. 2010 Aug 18;66(9):m1124–5. doi: 10.1107/s1600536810031922.
    参考文献:10.1107/s1600536810045368
    摘要:Gao X, Zhu M. Benzoic acid-2,2'-biimidazole (2/1). Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 10;66(Pt 12):o3124.
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