CAS: 4107-65-7; 2,4-Dimethoxybenzonitrile

上下游产品

2-hydroxy-4 methoxybenzonitrile dimethyl sulfate hydrogen cyanide 1,3-Dimethoxybenzene 2,4 dimethoxybenzoic acid N,N,N,N,N,N-hexamethylphosphoric triamide 2,4-Dimethoxybenzylamine 4-(2,4-dimethoxybenzoyl)-2H-spiro

2,4-二甲氧基甲苯置于sodium Azide,Copper(Ll) Sulfate Pentahydrate,碘苯二乙酸体系中,用 乙腈 作为反应溶剂,以96%的收率获得产物2,4-二甲氧基苯甲腈
参考文献:室温下将甲基芳烃直接转化为芳基腈
标题:室温下将甲基芳烃直接转化为芳基腈
摘要:在温和和中性条件下,甲基芳烃直接转化为芳基腈时,三个ch键被裂解(参见方案).这种新的合成工具不仅可用于构建合成和医学上重要的芳基腈,而且还可以在温和的条件下实现ch官能化.pida =苯基乙酸二乙酸铵.
DOI:10.1002/anie.200903838

专利信息

专利号:US-2004002613-A1
优先权日:2002-05-15
标 题 :Synthesis of benzonitriles from substituted benzoic acid

专利号:US-2004082796-A1
优先权日:2002-05-15
标 题 :Synthesis of substituted thiazoline carboxylic acids

专利号:US-2006217561-A1
优先权日:2002-05-15
标 题:Synthesis of substituted thiazoline carboxylic acids

专利号:US-7569606-B2
优先权日:2006-01-26
标 题 :Platinum complexes with mononitrile-containing ligands
发明人：XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 )which can be hydrolyzed iii vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

专利号:WO-2013001088-A1
优先权日:2011-06-30
标 题 :Direct synthesis of 18f-fluoromethoxy compounds for pet imaging and the provision of new precursors for direct radiosynthesis of protected derivatives of o-([18f]fluoromethyl) tyrosine

专利号:CN-104884427-A
优先权日:2012-10-15
标 题:Compounds that can be used in the synthesis of benzamide compounds