CAS: 3031-66-1; Hex-3-Yne-2,5-Diol

相似化合物

27301-54-8 142-30-3 42969-65-3

上下游产品

CAS号75-07-0 乙醛 | CAS号74-86-2 乙炔 | CAS号9004-34-6 微晶纤维素 | CAS号31556-90-8 (2R,3E,5S)-3,4-... | CAS号2028-63-9 3-丁炔-2-醇 | CAS号64-17-5 乙醇 | CAS号176042-55-0 3,4-dibromo-hex... | CAS号32570-88-0 2,5-二甲基-1-(2-吡啶基)吡咯 | CAS号110-13-4 2,5-己二酮 | CAS号625-86-5 2,5-二甲基呋喃 | CAS号38484-55-8 (2S,5R)-2,5-Hex... | CAS号17299-07-9 (2R,5R)-2,5-己二醇 | CAS号34338-96-0 (2S,5S)-2,5-己二醇 | CAS号3848-24-6 2,3-已二酮 | CAS号4437-51-8 3,4-己二酮 | CAS号5044-23-5 1-(4-氯苯基)-2,5-二甲基吡咯 | CAS号5044-27-9 1-(4-甲氧基苯基)-2,5...

Trans-3,4-Dibrom-Hexen-(3)-Diol-(2,5)置于锌体系中,用 乙醇 用作溶剂,化学反应 10.0H,反应生成3-己炔-2,5-二醇
参考文献:Hill,Richard K.; Pendalwar,Shekhar L.; Kielbasinski,Karen,Synthetic Communications,1990,Vol. 20,# 12,P. 1877-1884
标题:Hill,Richard K.; Pendalwar,Shekhar L.; Kielbasinski,Karen,Synthetic Communications,1990,Vol. 20,# 12,P. 1877-1884

专利信息

专利号:WO-0078725-A1
优先权日:1999-06-18
标题 :Synthesis of substituted amidines
发明人：CHOUEIRY DANIELE; GIRAUD DANIEL LIONEL; SCHOTTEN THEO
权利人:LILLY CO ELI; CHOUEIRY DANIELE; GIRAUD DANIEL LIONEL; SCHOTTEN THEO
摘要:The present invention provides a process for preparing amidines starting from carboxylic acid derivatives, in which the carboxylic acid containing moiety is attached to a sp3-, or sp?2- or sp1¿-hybridized carbon atom. The sp2-hybridized carbon atom, to which the carboxylic acid containing moiety is attached to may be part of an aromatic or heteroaromatic or olefinic system.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-11679182-B2
优先权日:2019-02-20
标题 :Methods of synthesis for a thioketal diol
发明人：HARRINGTON ROGER E; JACOBS JERBRENA C; DOYLE ROBERT
权利人:WARSAW ORTHOPEDIC INC
摘要:A method of making a hydroxyl-terminated thioketal diol is provided, the method comprising reacting a thioketal ester with a non-pyrophoric reducing agent to form a hydroxyl-terminated thioketal diol. The hydroxyl-terminated thioketal diol can be 2,2-(propane-2,2-diylbis(sulfanediyl)) diethanol. The non-pyrophoric reducing agent can be a sodium aluminum hydride, for example, sodium bis (2-methoxyethoxy)aluminum hydride. The thioketal ester can be dimethyl 2,2-(propane-2,2-diylbis(sulfanediyl)) diacetate. A biodegradable matrix prepared by reacting a hydroxyl-terminated thioketal diol with an isocyanate is provided. A method of making a biodegradable polyurethane composite is also provided.

专利号:US-6583315-B2
优先权日:2000-12-23
标 题:Process for preparing ethanebis(alkylphosphinic) acids
发明人：SICKEN MARTIN; WEFERLING NORBERT; SCHMITZ HANS-PETER
权利人:CLARIANT GMBH
摘要:The invention relates to a process for preparing ethanebis(alkylphosphinic) acids by n a) reacting elemental yellow phosphorus with alkyl halides in the presence of alkali metal hydroxide or of alkaline earth metal hydroxide to give a mixture whose main constituents are the alkali metal salts and/or alkaline earth metal salts of alkylphosphonous, phosphorous, and hypophosphorous acid, n b) liberating alkylphosphonous, phosphorous, and hypophosphorous acid by adding mineral acids, and also at the same time precipitating the alkali metal ions and, respectively, alkaline earth metal ions in the form of their salt of the mineral acids, and then n c) esterifying the alkylphosphonous acid from the mixture of the alkylphosphonous, phosphorous, and hypophosphorous acid, n d) isolating the ester of alkylphosphonous acid from the mixture and hydrolyzing the same to give alkylphosphonous acid, and n e) preparing, from the alkylphosphonous acid, the corresponding ethanebis(alkylphosphinic) acid of the general formula (I) where R 1 and R 2 may be identical or different and are hydrogen, a carboxy group, a carboxylic acid derivative, an unsubstituted or substituted alkyl group having from 1 to 10 carbon atoms, phenyl, benzyl, or alkyl-substituted aromatics, and R 3 and R 4 are identical or different and are an unsubstituted or substituted alkyl group having from 2 to 20 carbon atoms, by free-radical-initiated reaction with alkynes, and also to the use of the ethanebis(alkylphosphinic) acids prepared by this process as starting material for preparing flame retardants and precursors for the synthesis of other phosphorus-containing compounds.

专利号:US-4001305-A
优先权日:1974-02-04
标 题:Rf-glycols containing two perfluoroalkylthio groups and useful compositions therefrom
发明人：DEAR ROBERT ERNEST ARTHUR; FALK ROBERT ALLAN
权利人:CIBA GEIGY CORP
摘要:Perfluoroalkylthio glycols and esters thereof can be prepared by the free-radical catalyzed addition of a perfluoroalkylthiol to an acetylenic alcohol or ester thereof. The compounds obtained are useful intermediates for the synthesis of fluorochemicals with low free surface energies having oil and water repellent properties. In one embodiment, a perfluoroalkylthio glycol can be reacted with a diisocyanate to obtain a polyurethane containing perfluoroalkylthio groups, which polyurethanes are useful as coatings to provide oil and water repellence to textiles and as additives to plastics to provide mold-release and other desirable properties.

专利号:CN-102875332-A
优先权日:2012-10-12
标 题 :Synthesis of 3-hexyne-2,5-diol by slurry bed low pressure method