CAS: 22980-09-2; 2-(1H-Indol-3-yl)-2-Oxoacetyl Chloride

上下游产品

indole oxalyl dichloride 3-indolylglyoxylic acid 4-methoxy-1H-indole1-(1H-indol-3-yl)-2-(piperidin-1-yl)ethane-1,2-dione 1-(1H-indol-3-yl)-2-morpholinoethane-1,2-dione 2-(3-indolyl)oxoacetic acid methyl ester ethyl 2-(1H-indol-3-yl)-2-oxoacetate

📜吲哚置于草酰氯体系中,用 乙醚 用作溶剂,化学反应 3.0H,反应生成吲哚-3-乙醛酰氯
参考文献:N-Substituted Indole-3-Glyoxylamides Having Anti-Asthmatic,Antiallergic And Immunosuppressant/immuno-Modulating Action
标题:N-Substituted Indole-3-Glyoxylamides Having Anti-Asthmatic,Antiallergic And Immunosuppressant/immuno-Modulating Action
摘要:这项发明涉及新型n-取代吲哚-3-甘氨酰胺,以及它们的制备过程和药用.这些化合物具有抗哮喘,抗过敏和免疫抑制/免疫调节作用.

专利信息

专利号:US-7241900-B2
优先权日:2002-02-12
标题 :Synthesis of indole thiazole compounds as ligands for the Ah receptor
发明人：DELUCA HECTOR F; GRZYWACZ PAWEL K; SICINSKI RAFAL R
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is disclosed. A method of synthesizing aromatic ketone compositions of formula I comprising the step of ring synthesis of the tetrahydro-1,3-azoles of formula XI is also disclosed.

专利号:US-6133452-A
优先权日:1997-08-22
标题 :Synthesis of bisindolylmalimides
发明人：FAUL MARGARET MARY; WINNEROSKI JR LEONARD LARRY
权利人:LILLY CO ELI
摘要:The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is very efficient and robust macrocyclization methodology.

专利号:US-10081610-B2
优先权日:2014-09-12
标题 :Efficient and scalable synthesis of 2-(1′h-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs
发明人：SONG JIASHENG; ZHANG SUOMING; LI GUODONG; YANG LUQUING
权利人:ARIAGEN INC
摘要:Methods of synthesizing 2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) and structural analogs thereof. The methods include condensation reactions or condensation and oxidation reactions to form the thiazoline or thiazole moiety of ITE or its structural analogs.

专利号:US-5559228-A
优先权日:1995-03-30
标题 :Synthesis of bisindolylmaleimides
发明人：GILLIG JAMES R; JIROUSEK MICHAEL R
权利人:LILLY CO ELI
摘要:The present invention provides an efficient process of reacting a bis-indolyl acid of the Formula (II): (II) wherein R1 is a hydrogen or C1-C4 alkyl and R, X, and Y are optional substitutions; to produce a bis-indolyloxallic acid of the Formula (III): (III) Compounds of the Formula (III) are readily converted to the bis-indolylmaleimides.

专利号:US-5990319-A
优先权日:1996-08-23
标 题 :Synthesis of bisindolylmaleimides
发明人：FAUL MARGARET MARY; WINNEROSKI JR LEONARD LARRY
权利人:LILLY CO ELI
摘要:The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is a very efficient and robust macrocyclization methodology.

专利号:US-2004204588-A1
优先权日:2002-02-12
标题 :Synthesis of indole thiazole compounds as ligands for the Ah receptor