CAS: 224779-27-5; Tert-Butyl 5-Hydroxy-5,6-Dihydropyridine-1(2H)-Carboxylate

上下游产品

N-B°C-1,2,3,6-tetrahydropyridinetert-butyl 3-oxo-3,6-dihydropyridine-1 (2H)-carboxylate (+/-)-N-tert-butoxycarbonyl-5-(tert-butyldiphenylsilyloxy)-3-piperidene (3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)piperidine t-butyl (3R)-3-[(t-butyldiphenylsilyl)oxy]-3,6-dihydropyridine-1(2H)-carboxylate

📜1-Boc-4-甲烷磺酰氧基哌啶置于盐酸,碘代三甲硅烷,4-甲基苯磺酸吡啶,1,8-二氮杂双环[5.4.0]十一碳-7-烯,间氯过氧苯甲酸体系中,用 甲醇,二氯甲烷,乙酸乙酯,N,N-二甲基甲酰胺 用作溶剂,化学反应 57.0H,反应生成1-Boc-3-羟基-1,2,3,6-四氢吡啶
参考文献: Substituted Cyclic Compounds And Methods Of Use[fr] Composés Cycliques Substitués Et Procédés D'Utilisation
标题: Substituted Cyclic Compounds And Methods Of Use[fr] Composés Cycliques Substitués Et Procédés D'Utilisation
摘要:本发明提供了新颖的取代环化合物,药用可接受的盐及其制剂,用于调节蛋白酪氨酸激酶活性,并调节细胞活动,如增殖,分化,凋亡,迁移和侵袭.该发明还提供了包括这些化合物的药用可接受的组合物,以及在治疗哺乳动物,特别是人类的增生性疾病中使用这些组合物的方法.

专利信息

专利号:US-10906033-B2
优先权日:2016-03-28
标题 :Synthesis and application of chiral substituted polyvinylpyrrolidinones
发明人：HUA DUY H
权利人:UNIV KANSAS STATE
摘要:Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

专利号:US-10450282-B2
优先权日:2015-08-06
标题:Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols
发明人：OHLMEYER MICHAEL; ZAWARE NILESH; KASTRINSKY DAVID
权利人:ICAHN SCHOOL MED MOUNT SINAI
摘要:A process for the stereoselective synthesis of chiral 3-heterocyclyl-1,2-dihydroxy cyclohexanes is disclosed. The process involves reacting a tricyclic nitrogenous heterocycle with an allyl carbonate in the presence of a chiral palladium catalyst followed by oxidation of the olefinic bond to provide 3-heterocyclyl-1,2-dihydroxy cyclohexanes, cyclopentanes and corresponding alicyclic heterocycles. Also disclosed are methods for converting the heterocyclyl-1,2-dihydroxy cyclohexanes to 2-amino-6-(heteroaryl)cyclohexanols (and related cyclic compounds).

专利号:US-2020306737-A1
优先权日:2016-03-28
标 题:Synthesis and application of chiral substituted polyvinylpyrrolidinones

专利号:WO-2017172763-A1
优先权日:2016-03-28
标题 :Synthesis and application of chiral substituted polyvinylpyrrolidinones